Advancements in semen analysis and male fertility testing



In this episode of Backtable Urology, Dr. James Smith, Director of Male Reproductive Health at UC San Francisco and CMO of Fellow, discusses advancements in semen analysis and fertility testing with Dr. Jose Silva.

First, Dr. Smith introduces the significance of a comprehensive approach to examining male fertility, including total motile sperm counts and treatable conditions like prostatitis. He also highlights the role of the Fellow kit, a mail-in semen analysis test that improves the access and availability of sperm analysis. He explains the scientific foundations behind the Fellow kit, including temperature control, nutrient supply, and antibacterial measures to preserve sperm motility. The episode also touches on broader themes in fertility, such as the impact of illnesses like COVID-19 on sperm quality, the potential for future molecular and genetic testing in semen analysis, and the socioeconomic factors affecting access to fertility testing. Finally, Dr. Smith emphasizes the importance of early and comprehensive fertility evaluations for men and discusses the potential for future research to further improve fertility diagnostics.



semen analysis kit.webp


TIMESTAMPS

0:00 - Exploring Fertility Challenges and Solutions
10:16 - The Game-Changing Impact of the Fellow Semen Analysis Kit
15:29 - Navigating Semen Analysis: Quality, Progression, and Treatment
22:51 - The Importance of Early Fertility Testing and Intervention
27:27 - The Journey of Fellow: Improving Patient Compliance and Access
41:08 - The Future of Semen Analysis and Fertility Research
44:25 - Concluding Thoughts on Male Fertility and Patient Car
 
10:16 - The Game-Changing Impact of the Fellow Semen Analysis Kit


*reliable results within 2 days

*He also highlights the role of the Fellow kit, a mail-in semen analysis test that improves the access and availability of sperm analysis. He explains the scientific foundations behind the Fellow kit, including temperature control, nutrient supply, and antibacterial measures to preserve sperm motility
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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