39 & New To HCG Mono-therapy

[39andPrime]

Hi all! It’s refreshing to find a place to talk about these things with guys who have been there or are there currently. To start off I have average T and nothing really to complain about. However I have felt that I could use a boost if some kind. I have had intermittent bouts with ED and lack of desire (not always but some) I think much of my ED was due to penis dysmorphia… I just can’t shake that I have a tiny dock. However I know it’s not true - it ain’t big but it’s fine. Anyway mostly over that… did TRT in 2018 worst experience ever. It was just bad. Had a mental breakdown and quite immediately everything went back to normal.

A few months ago I heard of HCG mono therapy and read a lot of really great reviews on it. I’ve been doing it for 3 months and I feel improvement in a lot of areas. I seem harder when erect, I feel more full - I’m crossing my fingers their MIGHT be more size lol - anyway my desire has skyrocketed. 2-3x a month to 3-4X a week. The lady is digging it.

On the flip side I’ve felt heavy chested and lack of motivation in other areas. Not depressed, but a little moody. Right now my dosing is one shot 2000 UIL’s weekly. I am on half a pill of astronozle each week as well.

What are y’all’s thoughts on dosing? Should I split it up? Should I try cutting the astronozle out? I’m really wanting suggestions from people who have experienced it or are knowledgeable about it. My doctors great, but he’s more of just the script writer.

Also is there a chance at ALL that my package size could actually increase on this? Or is it just a firmer response orrrrr lol is it all just a placebo? Thanks for your input.

 

[Systemlord]

On the flip side I’ve felt heavy chested and lack of motivation in other areas. Not depressed, but a little moody. Right now my dosing is one shot 2000 UIL’s weekly.

That’s the thing with hCG sometimes, response is never like it would be on TRT. Your bad response to TRT being real bad has me wondering…

What was your TRT protocol back in 2018?

What are y’all’s thoughts on dosing?

That’s a little high at 2000 IU’s weekly, more like 1000-1500 IU’s weekly, but due to the half-life of hCG (24-36 hours), you should dose it at a minimum twice weekly.

In the majority of cases, you shouldn’t inject more than 500 IU’s at a time.

 

[39andPrime]

That’s the thing with hCG sometimes, response is never like it would be on TRT. Your bad response to TRT being real bad has me wondering…

What was your TRT protocol back in 2018?

That’s a little high at 2000 IU’s weekly, more like 1000-1500 IU’s weekly, but due to the half-life of hCG (24-36 hours), you should dose it at a minimum twice weekly.

In the majority of cases, you shouldn’t inject more than 500 IU’s at a time.

That’s the thing with hCG sometimes, response is never like it would be on TRT. Your bad response to TRT being real bad has me wondering…

What was your TRT protocol back in 2018?

That’s a little high at 2000 IU’s weekly, more like 1000-1500 IU’s weekly, but due to the half-life of hCG (24-36 hours), you should dose it at a minimum twice weekly.

In the majority of cases, you shouldn’t inject more than 500 IU’s at a time.

I’d have to go back and see if I can find that protocol. I do know that the majority of the time I feel great, but maybe splitting up my dosing would help even out a little bit and give me a more consistent steady vibe. I mean I crashed bad when I was taking the TRT. I’ll have to dig up that info tomorrow.

Thanks for the feedback on dosing though. I do think splitting it up would help in the long run. The pros do outweigh the cons, but I just want to feel more steady.

Also I don’t feel anxious I just get quiet and it’s done difficult to breathe at times. Again the gains are phenomenal just want to lessen the cons lol

 

[Systemlord]

I mean I crashed bad when I was taking the TRT.

That’s pretty much what I expected, and if I correct, the problem isn’t the TRT, the problem is your doctor doesn’t know how to prescribe it.

Right now my dosing is one shot 2000 UIL’s weekly.

If your TRT protocol is anything remotely similar to your hCG mono therapy protocol, it’s not hard to see why you’re having problems. The hCG is washes out of your system after a few days, leaving you high and dry for half of the week.

TRT should be dosed minimum once weekly, and even then the difference between peak and trough will be substantial, making twice weekly injections a better option and some men needing more shot frequency to eliminate the highs and low roller coaster feeling.

My first protocol was 200 mg every 3 weeks, crashed after one week. My co-workers witnessed it all, they would see me with lots of energy one week, the second week, they would ask me what’s wrong, they could see the crash on my face.

On weekly injections I crashed after 5 days, twice weekly crashed after 2 days and finally found daily dosing to produce the best results. You have to experiment with your protocol to find out what works.

From your description, I think you would feel better with a near flat hormone profile with minimal fluctuation in hormones.

 

[39andPrime]

Wow! I never thought about that. So do you think I should start doing 500 4x a week? Or what’s you

That’s pretty much what I expected, and if I correct, the problem isn’t the TRT, the problem is your doctor doesn’t know how to prescribe it.

If your TRT protocol is anything remotely similar to your hCG mono therapy protocol, it’s not hard to see why you’re having problems. The hCG is washes out of your system after a few days, leaving you high and dry for half of the week.

TRT should be dosed minimum once weekly, and even then the difference between peak and trough will be substantial, making twice weekly injections a better option and some men needing more shot frequency to eliminate the highs and low roller coaster feeling.

My first protocol was 200 mg every 3 weeks, crashed after one week. My co-workers witnessed it all, they would see me with lots of energy one week, the second week, they would ask me what’s wrong, they could see the crash on my face.

wow I never thought about that. Do you think I should start doing 500 3x a week? I “think” I love HCG but I want to be taking it in the dosage that’s right for me.

 

[Systemlord]

Do you think I should start doing 500 3x a week?

Yes, that would be much better, but without a Total T, Free T and estrogen level, as far as dosing is concerned, we are shooting in the dark.

If you change to this protocol, I think you’ll be feeling a lot better in less than a week.

 

[bixt]

Even 500 IU EOD

 

[Kenp]

That’s the thing with hCG sometimes, response is never like it would be on TRT. Your bad response to TRT being real bad has me wondering…

What was your TRT protocol back in 2018?

That’s a little high at 2000 IU’s weekly, more like 1000-1500 IU’s weekly, but due to the half-life of hCG (24-36 hours), you should dose it at a minimum twice weekly.

In the majority of cases, you shouldn’t inject more than 500 IU’s at a time.

Why shouldn't one inject more than 500 IU's at a time?

 

[FunkOdyssey]

Wow! I never thought about that. So do you think I should start doing 500 4x a week? Or what’s you

wow I never thought about that. Do you think I should start doing 500 3x a week? I “think” I love HCG but I want to be taking it in the dosage that’s right for me.

Based on what you've shared with 2000 producing sides, I think I would try 500iu every other day for a total of 1750 weekly.

 

[39andPrime]

Based on what you've shared with 2000 producing sides, I think I would try 500iu every other day for a total of 1750 weekly.

Great call! That’s exactly what I’m going to try. Thank you

 

[Systemlord]

Why shouldn't one inject more than 500 IU's at a time?

This is what Dr. Crisler used to say, who had a lot of experience prescribing it. A lot of the time, you’ll just end up spiking estrogen really high.

 

[Nelson Vergel]

This is what Dr. Crisler used to say

Did he say that for monotherapy? He referred to TRT+hCG

@39andPrime
Maybe I missed it. Have you posted labwork results? Testosterone, total and free?

 

[39andPrime]

Did he say that for monotherapy? He referred to TRT+hCG

@39andPrime
Maybe I missed it. Have you posted labwork results? Testosterone, total and free?

Most men cannot attain testosterone levels over 500-600 ng/dL with a 2000 IU weekly shot of hCG. I would be surprised if your T was even 300 right before the injection.

I just had lab work done & should have results by tomorrow. I’ll post as soon as I do! Thanks for the info.

 

[Nelson Vergel]

"The study included 20 men. The average age was 50.3 (SD 15.6) years and ranged from 26 to 77. On past medical history, 2 of the patients had a history of anabolic steroid use, and two had a history of prostate cancer, one of whom was post- -radical prostatectomy. These patients had an average testicular volume of 14.2cc (SD 4.3), and 3 presented with varicoceles, 2 of which were grade II and 1 of which was grade I (Table-1). Indications for treatment were largely attributed to persistent complaints of one or multiple of either low libido, low energy, or erectile dysfunction, but also included infertility and insomnia. Patients received an average dose of 2000 IU weekly."

These men presented with an average initial T of 361.8 ng/dL (SD 158.2) and improved to an average follow-up T of 519.8 ng/dL (SD 265.6). The duration of therapy for these men averaged 6 months, with an average weekly hCG dose of 2000 IU. Over this period, they experienced an average change in T of 60%. One-tail Mann Whitney U test demonstrated this improvement was significant, as the sample of T at baseline was significantly less (p<0.005) than that of follow-up T. This corresponded with 50% of men subjectively reporting symptom improvement. Of the 10 men who reported symptom improvement, only 2 had negative changes in testosterone levels, both by less than 15%.

Using Human Chorionic Gonadotropin (HCG) alone for the treatment of men with low testosterone.

Human Chorionic Gonadotropin monotherapy for the treatment of hypogonadal symptoms in men with total testosterone > 300 ng/dL. Madhusoodanan V, Patel P, Lima TFN, Gondokusumo J, Lo E, Thirumavalavan N, Lipshultz LI, Ramasamy R Human Chorionic Gonadotropin monotherapy for the treatment of...

www.excelmale.com

I would use 1,000 IU three times per week of hCG monotherapy or

TRT (100-150 mg/week injections or higher concentration compounded creams) plus:

1- 500 IU hCG three times per week (If I want to get my girl pregnant) Best HCG Dose for Men on TRT: Two Studies That Used HCG with Testosterone

or

2- 500 IU hCG twice per week if I just want to prevent testicular atrophy.

 

[Nelson Vergel]

hCG monotherapy response depends on:

1- Age (older patients don't respond as well).

Time on TRT and Age Predict HCG Response

Abstract from AUA2016.org Duration of Testosterone Therapy and Male Age Predict Time to Return of Normal Total Motile Sperm Count after Human Chorionic Gonadotropin Therapy Authors: Taylor P. Kohn*, Matthew R. Louis, Stephen M. Pickett, Mark C. Lindgren, Alexander W. Pastuszak, Larry I...

www.excelmale.com

2- Initial testicular size

Gonadotropin therapy in men with isolated hypogonadotropic hypogonadism: the response to human chorionic gonadotropin is predicted by initial testicular size - PubMed

This study was designed to determine whether exogenous hCG alone can complete spermiogenesis in men with isolated hypogonadotropic hypogonadism (IHH). hCG was administered to 22 men with IHH until maximal testicular growth was achieved. Their mean testicular volume increased from 5.5 +/- 1.1...

pubmed.ncbi.nlm.nih.gov

3- Dose and frequency.
4- How much one tolerates or experiences water retention/high blood pressure.
5- How much money and access you have (hCG is now expensive since the FDA made it illegal for compounding pharmacies to make it)

The FDA Ended Your Access to More Economical hCG and FSH

UPDATE ON DECEMBER 1, 2021: The FDA has just made it a lot more difficult for couples seeking fertility to start a family. They have shut down the only affordable access to fertility hormones made by compounding pharmacies for over 40 years . All compounders were ordered to stop making...

www.excelmale.com

My protocol (for testicular size and libido, NOT fertility)

Nelson Vergel 's Testosterone plus HCG Protocol

The Use of HCG to Prevent / Reverse Testicular Shrinkage and Preserve Fertility • HCG (human chorionic gonadotropin) is produced by human placenta, sterile product derived from urine of pregnant females. Recombinant DNA formulas are produced by pharmaceutical companies and compounding...

www.excelmale.com

 

[Systemlord]

Did he say that for monotherapy? He referred to TRT+hCG

I don’t recall if that was on TRT and or hCG mono therapy.

Definitely for PCT’s/fertility protocols you may want to run higher dosing.

 

[Nelson Vergel]

Definitely for PCT’s/fertility protocols you may want to run higher dosing.

Agreed