Nelson Vergel 's Testosterone plus HCG Protocol

Nelson Vergel

Founder, ExcelMale.com


The Use of HCG to Prevent / Reverse Testicular Shrinkage and Preserve Fertility

• HCG (human chorionic gonadotropin) is produced by human placenta, sterile product derived from urine of pregnant females. Recombinant DNA formulas are produced by pharmaceutical companies and compounding pharmacies.

• In men HCG mimics LH from pituitary to stimulate Leydig cells of testes to produce testosterone.

• It can have an additive effect to testosterone replacement therapy's ( TRT) increases in estradiol, hematocrit and/or acne

• Normal lyophilized vial contains 5,000 or 11,000 units HCG by compounding pharmacies (commercial products cost 3X compounding). The vial is sent with bacteriostatic water for reconstitution.

• Used by fertility specialists to induce ovulation to harvest eggs, and sperm production.

• Latest data show that men on TRT + HCG were able to remain fertile. (TRT + 500 IU HCG every other day)

• Usual dose of 350-500 IU two times a week for prevention/reversal of testicular atrophy. No data have been published on this use.

• Anecdotal effect on raising sex drive in men. No data.

• HCG acts as a Leydig cell stimulator and cell volumizer. Testicles regain size but do not grow beyond baseline size.

• Continuous testosterone can reduce fertility in over 50% of TRT users and testicular size by 10-30 % . HCG may reverse those two issues.

• Noticeable testicular size reduction can be a more common complaints in men with smaller testicular size at baseline. May not be important to some older men or men not worried about fertility.

• HCG may be used in patients who have abused steroids for 6-8 weeks before clomiphene to attempt to accelerate natural production of testosterone.

• May be used in younger males as sole method of testosterone treatment with secondary hypogonadism. All men respond differently to HCG in ability to boost T production by testes. Expensive as monotherapy and frequently used with testosterone replacement since that combination may be more cost effective in normalizing testosterone and fertility.

. HCG may reactivate upstream hormones like pregnenolone and progesterone that are shut down by testosterone replacement therapy.

• HCG may not work well in some men who have primary hypogonadism, i.e. dysfunction of the Leydig cells in the testes.

 

jackass69

New Member
So I can inject both my testosterone and hcg in the same needle? Sorry I am new to this. I just received everything in the mail today from Defy Medical.
 

Vince

Super Moderator
So I can inject both my testosterone and hcg in the same needle? Sorry I am new to this. I just received everything in the mail today from Defy Medical.
Yes you can, I did that for one year. Now I use two syringes, because I increased my dose.
 

Vince

Super Moderator
What is the best way to dose it without spiking E2?
I doubt that adding 350-500 IU HCG twice per week to TRT increases estradiol by more than 10-20 %

Here is what happens with a large dose of 3000 IU per day for 3 days. Estradiol first peaks one day after first injection and then goes down even during the third day. So, there is a stabilization after the first dose. These levels are measured using the immunoasssay that overestimates estradiol, so probably visualize these values 30% lower (assumption).

If you have any doubt, do an experiment on yourself by measuring estradiol before and after 2 weeks on whatever dose you use.


View attachment 2136

Source: https://www.jstage.jst.go.jp/article/endocrj1954/22/4/22_4_287/_pdf
a post from Nelson
 
Ok so if you been on TRT by itself for 2 years(gels) will HCG bring back the size, ejaculate volume, and sperm?
No one can possibly say yes, or no, if you've been shut down all this time it may not be recoverable but you'd have to try at probably 500iu 3X per week and just have to play it out and see what happens.
 

Blackbond07

New Member
Ok I'm about to have all the tests ran thru defy medical. I want to see if there is any way to get the boys back swimming!
 

Vonko1988

Member
I cannot draw them together in the same needle. From Nelson's video it is not very clear how to do that. I got the impression he puts air in between but Im not sure.
I tried to fill the 29G needle with test first, but when I tried to add the hcg on top big air bubbles formed and it became a mess. For now I see no choice but to make two separate injections :(

@Nelson Vergel can you make some more detailed video explaining how to technically draw them together in the same syringe, which should be first, how to manage the bubbles, does the needle with a few drops of testosterone outside will damage the hcg in the bottle?
 

rayrock1

Member
yes I tried the same procedure and had Test bubbling out the tip on the needle before trying to add the hcg. If I draw down air in between, now I have an air pocket in the syringe that I can not calibrate the exact amount of hcg. Any suggestions? or tips, thanks
 

Cataceous

Well-Known Member
I've done hundreds of these dual-drug, single-syringe injections, and what works for me is to alternate which drug is drawn first. You start by injecting air into the first vial. The injected air volume should be slightly more than double the size of the normal drug withdrawal. Next you draw the drug from this vial. After this you immediately draw the normal volume of the second drug from the second vial without pre-injecting air. Finally, inject as usual. When it's time for the next dose you repeat the procedure, except you reverse the order of the drugs. In this way you avoid overly low pressure in either vial that might suck the first-drawn drug into it. It's preferable to avoid overshooting the second draw, because pushing back the second drug may cause some cross-contamination of the vial with the first drug.

When a water-based drug such as hCG is drawn second after an oil-based drug you may see "bubbles" appearing in the oil. But this is not air. The water is heavier than oil, so its droplets tend to penetrate the oil, giving the appearance of bubbles. This is not a problem, and you should simply make sure that the volume in the syringe after the second draw is the sum of the desired volumes for the two drugs.

Example: Suppose the normal doses are 0.2 mL of testosterone cypionate and 0.1 mL of hCG. For the first injection you inject a hair over 0.4 mL of air into the cypionate vial and then withdraw 0.2 mL of the cypionate. Next you draw 0.1 mL from the hCG vial. The syringe should now contain 0.3 mL in total, which you inject as usual.

For the second injection you start by injecting a hair over 0.2 mL of air into the vial containing hCG and then draw 0.1 mL of hCG. Next, you draw 0.2 mL from the testosterone vial, without an air pre-injection. Once again the syringe has 0.3 mL of the two drugs, which you inject.

For the third injection you are back to cypionate as the first drawn, and so on.

On average this procedure keeps the internal pressures of the two vials close to local air pressure, or slightly above. The stickler for detail may note that the vial used second for the first injection may stay slightly under-pressure. But this can be fixed with additional air during the draw for the second injection, or alternatively just make sure your hCG remains pressurized when you originally add water to it, and use it second for the first injection.
 

adshan

New Member
My doctor prescribed testosterone to go into the muscle but HMG and HCG subaqueous. Should I mix them together and inject all into the muscle?
 

Cataceous

Well-Known Member
My doctor prescribed testosterone to go into the muscle but HMG and HCG subaqueous. Should I mix them together and inject all into the muscle?
I assume by "mix" you mean draw separately into the same syringe. Definitely don't attempt a literal mixing, as oil- and water-based drugs will not mix. With both drugs in the same syringe you can inject either intramuscularly or subcutaneously. If the testosterone volume is large then intramuscular injections may be preferred. Otherwise you may think it's better not to poke holes in your muscles, and therefore stick with subcutaneous injections.
 
I assume by "mix" you mean draw separately into the same syringe. Definitely don't attempt a literal mixing, as oil- and water-based drugs will not mix. With both drugs in the same syringe you can inject either intramuscularly or subcutaneously. If the testosterone volume is large then intramuscular injections may be preferred. Otherwise you may think it's better not to poke holes in your muscles, and therefore stick with subcutaneous injections.
Do you do subcutaneous?
 

Forty2

Member
I assume by "mix" you mean draw separately into the same syringe. Definitely don't attempt a literal mixing, as oil- and water-based drugs will not mix. With both drugs in the same syringe you can inject either intramuscularly or subcutaneously. If the testosterone volume is large then intramuscular injections may be preferred. Otherwise you may think it's better not to poke holes in your muscles, and therefore stick with subcutaneous injections.
Does it matter which order you draw each into the syringe? Could it be better to have the quickly absorbing water based HCG enter the site first?
 

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