* Once a patient is established on therapy, both the AUA and the EAU identify a HCT level of 54%, as the level at which intervention is warranted. Neither framework offers a step-by-step approach for responding should the HCT begins to rise or the sequence and timing of necessary actions.
*...
I have a high Hematocrit of 54 percent, Low ferritin of 29 and my estradiol senstive level is 11. I have been extremly tired with brain fog. What could be the most likely culprit??
I've been on a twice weekly testosterone cypionate IM injection protocol for over 10 years. Latest protocol was 100mg (0.5ml) twice a week. My TT, FT and Estradiol, Sensitive numbers are great with this protocol, but eventually I need to donate blood when my Hematocrit gets too high.
My Doctor...
Can anyone make sense of this? Felt increasingly more fatigued past couple months since switching to cream... I was doing 200mg to scrotum per day split, that got me too high , over 1000 TT. Then went to 100mg leg, 100mg scrotum and was still too high at 850 TT (my shbg is 9.5 so FT always...
What's the consensus on Iron supplementation while on TRT? Is it a good thing or a bad thing to do? I'm currently taking Ferosom Forte powder to try to get my Iron back in the normal range but also don't want HCT to skyrocket.
Let me know what works for you.
Thanks
Funkybeats
Abstract
INTRODUCTION AND OBJECTIVES:
The relationship between testosterone replacement therapy (TRT) and obstructive sleep apnea (OSA) is an emerging field of interest. TRT is typically contraindicated in patients with severe uncontrolled OSA, but our previous research has shown OSA risk...
* approximately 30-50% of patients with hypertension have obstructive sleep apnea but as many as 80% of those with resistance hypertension have sleep apnea
Drs Marwah Abdalla and Susan Redline discuss when to suspect sleep apnea; how to approach screening, diagnosis, and treatment; and how...
How often should men on TRT check their hematocrit?
The standard monitoring schedule includes a baseline CBC before starting TRT, a recheck at 3 to 6 weeks, another at 3 months, and then at 6 and 12 months once stable. Any dose or formulation change resets the monitoring clock, requiring a...
I got my first full lab work done in almost 6 months, and got the results back today. For almost 7 weeks before these labs, I lowered my weekly dose from 100mg, to 84. I inject three times a week. This blood draw was done at a 49 hour trough after my last injection. You can see my total T has...
Is there a reduction in the maximum recommended hematocrit value as a function of coronary calcium score? I currently have a 52.8 hematocrit with a past CAC score of 153.
* 100 patients were identified as first-time TRT users, with 50 in the subcutaneous group and 50 in the intramuscular group. There was no significant difference in age, pre-TRT testosterone levels, pre-TRT hematocrit levels, or post-TRT hematocrit levels. There was a significant difference in...
* Erythrocytapheresis is a procedure during which blood is passed through a blood cell separator that separates red blood cells (RBCs) from other components. The RBCs are replaced by a crystalloid or colloid solution when necessary [1]. The procedure is principally used to treat erythrocytosis...
Erythropoiesis is the scientific term for the production of red blood cells, also known as erythrocytes. These essential cells are responsible for transporting oxygen throughout the body. They originate from stem cells in the bone marrow, the spongy tissue inside bones that serves as the body's...
About 2 weeks ago I had my labs drawn at Labcorp and I was surprised that my hemoglobin and hematocrit were this elevated with a 786 testosterone level. Each week I take a total of 90 mg/ml of cypionate by taking daily subcutaneous injections. My recent labcorp labs:
Blood Pressure 122/72...
Hey guys,
I’ve been on 100mg Test Cyp IM weekly for the past 15 years, started at 25 I'm now 40 with good results overall, but something’s changed recently and I need experienced eyes on this.
For the past month, I’ve had constant lightheadedness, faint feelings, brain fog, and general weakness...
Has anyone tried this? One of my coaching clients had a 7 point drop in hematocrit.
https://leviathan-nutrition.com/products/new-leviathan-hemo-flow-hematocrit-blood-viscosity
FREQUENTLY ASKED QUESTIONS
WHAT DOES HEMO FLOW DO? HEMO FLOW addresses the rampant issue of high hematocrit...
Briefing Document: Optimizing Hematocrit Control in Testosterone Therapy
Source: Excerpts from "From Phlebotomy to Formulation: Optimizing Hematocrit Control in Testosterone Therapy - Excel Male TRT Forum"
1. Executive Summary
Testosterone Replacement Therapy (TRT) offers significant benefits...
Fig 1: Change in hematocrit at 12, 48, 72 and 96 months in men receiving testosterone therapy vs. untreated men.5
* Hematocrit levels show significant increase (+4% at month 96) in men receiving TTh. This increase occurred during the first 48 months, as illustrated in figure 1. Final...
This was a very interesting experiment. After struggling with high hematocrit on enanthate—despite changing injection frequency, switching between subq and IM, and adjusting my dosage—I decided to test daily injections of testosterone propionate. My theory was that a shorter-acting ester would...
https://www.physiciansweekly.com/frequency-of-testosterone-induced-erythrocytosis-in-trt/
The following is a summary of “Prevalence and predictive factors of testosterone-induced erythrocytosis: a retrospective single center study,” published in the January 2025 issue of Endocrinology by...
Been on for about 10 months and have tried multiple frequencies, administration sites, and dosages.
All of these trials were based on the need to control elevated H&H. The one that did the trick in mitigating it was daily subcutaneous injections totaling 70mg/week. Labs for this protocol were...
60 year old male here. I have been on test cyp for 15 years. I have always struggled with elevated hematocrit and I dislike donating blood.. I lowered my dose to 12mg sub-q every other day. On that dose my hematocrit stayed around 49-50 area. Been doing that for a few years but I just don't feel...
After having issues with injection absorption, I recently switched to testogel and the results have been surprisingly good. Using the technique of showering, exfoliating and applying lotion, it feels like my levels have skyrocketed and stay elevated well into the next day. I am pretty sure that...
I recently donated whole blood, my labs are coming up in several weeks and I'm hoping that improved eating habits and donating will lower Hgb/Hct levels several points. Question, would donating double red blood cells help to lower Hct levels more than donating whole blood? Not make a difference...
https://academic.oup.com/jcem/advance-article-abstract/doi/10.1210/clinem/dgae434/7697829?redirectedFrom=fulltext&login=false
Conclusions
We conclude that hypogonadal men have reduced erythrocyte lifespan and acute androgen-induced increase in circulating erythrocyte lifespan may contribute...
https://www.thebloodproject.com/cases-archive/testosterone-therapy-and-erythrocytosis-2/
Introduction
Androgens play a crucial role in the development and maintenance of:
Male reproductive and sexual functions
Body composition
Erythropoiesis
Muscle and bone health
Cognitive function...
ABSTRACT
Objective
Elevated hematocrit (Hct) can result in increased risk of major adverse cardiac events(MACE) in men receiving testosterone therapy (TTh). However, the impact of the magnitude of the change in Hct from baseline after starting TTh has never been assessed.
Methods
To assess...
I've finally gotten my results back and here they are (3 mth f/u):
TT - 990 (MS)
FT - 178 (Dialysis)
Estradiol - 44 (LC/MS)
Free T3 - 3.2
SHBG - 37
Hematocrit - 54
Hemoglobin - 17.2
LH - <0.2 Reference Range: 1.5-9.3 mIU/mL
I'm feeling great and I would not change anything in my protocol...
Shane M. Kelleher,
*InfiniT Men’s Health Clinic, Burleson, TX76028, USA
Abstract
The goal of this study was to determine how to minimize the secondary polycythemia effect observed in patients on testosterone replacement therapy (TRT). Patient hemoglobin, estradiol (E2), and total...
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