estrogen

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  1. G

    Seeking clarification from AI opponents

    Since I do want to sign up for jay Campbell's 50$/month forum to maybe get access to Dr. Keith Nichols, Dr. Rob etc. I will post these questions here. This is not intended to invite argument for/against aromatase inhibitor usage. I simply want to understand the perspective of AI opponents...
  2. S

    Arimidex discontinuation update

    So for about the past month I had weaned off of arimidex in hopes of feeling better. I was using the 1mg adex/100mg test strategy prior to weaning off. E2 was around 21 and tt was at 1000ish. Felt awful, no sex drive, fatigue, aches and pains, hair shedding, mentally slow, brain fog, dark...
  3. T

    Exogenous Estrogen in Men

    Old study that looked at exogenous estrogen (among other things) in men targeted at reducing mortality due to cardiac events: The Coronary Drug Project: findings leading to discontinuation of the 2.5-mg/day estrogen group. The purpose of the Coronary Drug Project, a national collaborative...
  4. D

    Ditch your AI now - you don't need it!

    I'm a long time lurker and haven't posted much (perhaps even never) but I felt I should contribute something in return: I have very mild gyno that I've had most of my life. As soon as my E2 goes up it starts getting sore. That's when I USED to take an arimidex and it would go away. This time...
  5. E

    Could tiredness be a symptom of high e2?

    So Ive been listening to that jay campbell show where they tell you AI is poison and "very bad for biological systems". So I decided to try without it. 8 weeks now and Im so fucking tired I dont know what to do. Not only that, but I have ED and libido is low. Isnt AI supposed to be bad? So...
  6. J

    24 years old,0 libido for 2.5 years HELP

    Hello everyone! I just want to say that I am not on trt, or ever took some kind of steroid or drug or something like that. After starting natural bodybuilding in my teens, I felt great at 18-21 years old, I had an easy time putting on muscle and getting pumps, libido was sky high, agression and...
  7. J

    Exogenous Estrogen

    39yrs old, 260lbs Iinitial labs had estradiol at 127.4 pg/ml) Began aromasin at 12.5mg 3x wk Two weeks later labs failed to detect estradiol (<2.5 pg/ml). In other words, crashed. Empirical symptoms consistent with low estrogen. This is not the first time I’ve crashed my estrogen to...
  8. D

    The answer to high levels of aromatase?

    Hi all, Long time reader, first time poster. I've just come across some research which I don't believe has been discussed on here previously, and after posting in the TRT Australia group, thought certain members of this forum might find this interesting/useful. Background: 26 yrs old Lean...
  9. DragonBits

    Estrogen and allergies: cost benefit analysis

    IMO estrogen is one of those hormones that have a cost benefit aspect. IMO the benefits out weigh the cost, but one should know about possible side effects of estrogen. Recently, I had allegoric reactions to amoxicillin and then to the eyedrops I had been using for a year, brimonidine. I...
  10. M

    Alternative to Anastrozole?

    Hi everyone, Been following my protocol of injecting once every 4 days with a half inch insulin syringe, intramuscularly into my legs, around the quads mostly. Sometimes into my glutes. I inject 50mg each time. I also inject 500iu of HCG every time I inject testosterone, but into my stomach...
  11. B

    Estrogen and dht ?

    Any of you have a concrete answer as to how dht blocks estrogen? Also how blocking dht raises estrogen?
  12. I

    Estrogen Question

    Does anybody know if Estrogen levels are higher prior to starting TRT? Say you were at 300 TT prior to starting and an E2 of 30. Is the E2 number affected at all due to TT being lower? What I’m wondering is if the E2 at start is where the body naturally wants to be and if we should be targeting...
  13. Z

    MWF protocol

    I just started this week on my new MWF 50mg each injection. The first week has been okay. I am going to avoid an AI if I can. I was just wondering if their are any members on here who do specifically 3 days a week and how it’s been going for them??? Thanks!
  14. Vince Carter

    What if what you knew about E in the trough is all wrong...

    What if you needed to monitor E2, in your PEAK, post injection. What if your trough LC/MS/MS was 40 and you thought that number was high and have reliable elevated E symptoms, when in reality your E was...50, 60, or twice that number after your injection. What if that's where your E problems...
  15. B

    Relationship Between Estrogen & Spleen Discomfort?

    Hey all, High SHBG guy here. Before I began treatment, I had a constant (not too bad, but annoying) discomfort/pain over my spleen for about six months. I saw a few doctors, but none of them could figure out what was wrong and said it may be psychosomatic. In May, I started on hCG and an A.I...
  16. Z

    Labs

    Here are my labs, I just started seeing a new doctor. These labs are from last doctor awhile ago. My main reason for posting them though, is I am wondering just how much or how little my PA was testing for... thanks.
  17. T

    Subcutaneous Split Transition - Complete Labs

    I posted a couple weeks ago, seeking advice on managing my dose, and transitioning from a 140mg weekly IM injection to a 70mg 2x weekly sub q regiment. I feel like my estrogen is somewhat stabile with .15 Arimidex at injection time. The labs support this notion. It’s only been a couple weeks...
  18. J

    How does high estrogen cause poor erections and low libido?

    Are there any scientific/medical explanations as to how and why high estrogen will cause weak erections or "up and down" erections and/or a poor libido? Also of note, why can PDE5 medications ( Cialis, Viagra ) mask or override high e2 and allow for a decent erection? Does high e2 do something...
  19. Z

    Someone please help really need advice and answers

    So I have posted on this board a few times over the last couple weeks. Real quick long story short. 2 Monday’s ago I took a dose of my AI ‘when my doctor told me not to take it anymore, I took it because I thought my e2 was getting high’ anyways fast foward to now. My libido is none existent. A...
  20. Z

    What Causes High DHT?

    I was just wondering what causes high DHT? I have read somewhere that it can be caused by low e2 which can cause “DHT rage”. Thanks!
  21. Dr. John Crisler

    TRT without the use of Aromatase Inhibitors

    As an Osteopathic physician, less drugs is better. To be clear, I wish we never had to add an AI to a gentleman's TRT regimen. Through this thread, let's explore this topic. I am especially interested in hearing from guys who previously were on an AI, then successfully discontinued it. At a...
  22. R

    How Much Cypionate For Reaching Optimal Testosterone Level

    Hi All. Me going to start this week on Friday with Testosterone Only I am Primary and want achieve Optimal Test Levels My details Age 41 Weight 75/77 kg Height 175cms TT 378 Shbg 50 Estradiol 38 Should I start with 100 MG splitting in a week and after 6 weeks after blood work ramp up dosage Does...
  23. Gianluca

    Animal products more likely than plant food to increase Estrogens in men and women?

    to start I'm not a vegan advocate but just like to consider the other side, for years I thought soy and flax seed would increase estrogens levels and I understand now they do not, but plants contain compounds like which are weaker than animal/human estrogen, when actually human and animals...
  24. J

    Does lowering E2 decrease SHBG?

    I just bought a testosterone booster that has a estrogen blocker in it called arimistane. Anyway I have been taking it for a couple days and really feel the test boost not only in the gym but in the sexual department as well. I def have stronger erections and my libido is better. I heard...
  25. W

    Does E2 Reduce At The Same Rate As Testosterone?

    If testosterone dosage is reduced does your estrogen go down at the same rate (same amount of time) as your testosterone levels?
  26. G

    Should we monitor free estradiol E2 in men on TRT?

    I'll keep this simple. What matters is free test, not total. Free T3, not total. Free (active) Vitamin D, not total. Magnesium RBC, not serum total. I feel like the more we learn, the more we realize that the free, or active, form of hormones/ minerals is what matters. So is free E2 what really...
  27. I

    Trying to control E2 via Fat loss, Daily injections, Calcium D-Glucarate, Metforming and Cialis

    After reading/hearing about the dangers (especially bone loss) of long term Anastrozol usage I have committed myself to control E2 using the following approach: 1) Lose more body fat: Already lost 35-40kg, but need to lose around 5-10 more to get into the single digits. Some people report...
  28. G

    Thoughts on E2

    So I just had an interesting thought about E2 levels in men. So the gold standard in regards to where we want our hormones, is to get them to the levels that they were when we were in our prime, correct? So probably around 18-22, I would assume for most men, hormone wise at least. Take total and...
  29. DragonBits

    E2, effect of LC-MS/MS test, effect of BMI on TT not on E2

    Low Estradiol Concentrations in Men With Subnormal Testosterone Concentrations and Type 2 Diabetes This is an interesting study of men with T2 diabetes. It's interesting for several reasons outside of diabetes. 1) It directly compares the cheaper immunoassay Vs LC-MS/MS sensitive test for E2...
  30. 3

    Super dry skin (face only)...E2?

    I can't seem to find a definitive correlation to low or high E2, so here is what is going on. The last week or so I've developed really dry skin on my face and scalp. I used to have super dry skin before I started TRT, but after a couple of months on my skin was great, even slightly oily (no...
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