covid-19

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  1. madman

    Fulminating COVID-19 infection

    Abstract The author takes us on a very personal journey through his experience of a severe COVID-19 infection, hospitalization, and subsequent recovery, along with the sequelae. His experience and subsequent research have left him convinced of the value of phosphodiesterase type-5 inhibitors...
  2. A

    Low testosterone levels and high estradiol to testosterone ratio are associated with hyperinflammatory state and mortality in men with COVID-19

    https://pubmed.ncbi.nlm.nih.gov/34661247/ Eur Rev Med Pharmacol Sci . 2021 Oct;25(19):5889-5903. doi: 10.26355/eurrev_202110_26865. Low testosterone levels and high estradiol to testosterone ratio are associated with hyperinflammatory state and mortality in hospitalized men with COVID-19 M...
  3. P

    TRT (Testosterone Replacement) and COVID-19 Vaccine

    Any insight from the forum on TRT and the COVID-19 Vaccine? I am sure no Studies yet but just wondered on thoughts. There is evidence of T boosting the immune system. Curious about any interaction concerns? None listed on any of the vaccine info sheets. Thoughts?
  4. S

    Two New Drugs to Treat COVID-19 from Merck and Pfizer

    New antiviral drug completely suppresses SARS-CoV-2 transmission within 24 hours:
  5. S

    Bromelain inhibits COVID-19 in vitro by degrading/cleaving the viral spike protein and two host cell surface receptors

    Could pineapples be a new weapon against COVID-19: The Bromelain concentration tested was 75 micrograms/mL which might be achievable by supplementation. Still, this is only in vitro study in monkey kidney cells. It is not clear if the necessary concentration can be achieved in human lungs and...
  6. Vince

    A Supercomputer Analyzed Covid-19

    Earlier this summer, the Summit supercomputer at Oak Ridge National Lab in Tennessee set about crunching data on more than 40,000 genes from 17,000 genetic samples in an effort to better understand Covid-19. Summit is the second-fastest computer in the world, but the process — which involved...
  7. J

    Low Vitamin C Levels in Covid Patients

    A study showed that more than 90% of ICU patients with covid-19 had undetectable Vitamin C levels: "Plasma vitamin C levels in a population of adult ICU patients COVID-19 who met ARDS criteria according to the Berlin definition were prospectively measured. None of the patients included...
  8. S

    AeroNabs: a promising antiviral nasal spray against COVID-19

    ‘AeroNabs’ Promise Powerful, Inhalable Protection Against COVID-1:
  9. S

    Favipiravir: positive effect for mild to moderate cases of COVID-19

    Glenmark’s phase III favipiravir study finds drug speeds clinical improvement for some patients Favipiravir COVID-19 studies summary:
  10. J

    An Anabolic Steroid to Treat Covid-19?

    This is posted more for its amusement value rather than a serious suggestion for therapy. The IEEE Spectrum has posted an article on a new approach to treating COVID. It says: "One of the most persistent and deadly outcomes of extreme COVID disease involves the lungs of patients filling with...
  11. J

    Blood Test to Determine When to Use Steroids for Covid-19

    The use of corticosteroids to treat covid-19 has been controversial. Some studies has shown it benefits patients and others have shown it worsens the disease. A new study says that C Reactive Protein levels indicate when corticosteroid use is beneficial. High levels indicate they will help...
  12. Nelson Vergel

    Addressing male sexual and reproductive health in the wake of COVID-19 outbreak

    J Endocrinol Invest. 2020 Jul 13 : 1–9. Addressing male sexual and reproductive health in the wake of COVID-19 outbreak A. Sansone,1 D. Mollaioli,1 G. Ciocca,2 E. Limoncin,1 E. Colonnello,1 W. Vena,3,4 and E. A. Janninicorresponding author1 Abstract Purpose The COVID-19 pandemic, caused by...
  13. S

    Ivermectin and COVID-19

    Hello all, I want to share my personal experience with the use of Ivermectin for treatment of COVID-19. Three weeks ago I never even heard of this drug but today I consider it one of the most to be thankful for. There weeks ago I got a call from my son telling me he and his girlfriend have...
  14. S

    MMR vaccine may protect from COVID-19 complications

    The study shows a correlation: countries with a high vaccination rate of MMR vaccine show a lower COVID-19 death rate per 100 000 population. However, correlation studies are not capable of pinpointing the exact cause of reduced mortatlity - is it the MMR vaccine itself or something else that...
  15. Vince

    NIH has begun a study to determine who may have been exposed to COVID-19

    NIH has begun a study to determine who may have been exposed to COVID-19 and, as a result, has antibodies in their bloodstream. They are asking for volunteers. Here is the link with information: NIH Begins Study to Quantify Undetected Cases of Coronavirus Infection
  16. DragonBits

    Steroid dexamethasone reduces deaths with severe COVID-19

    This is cheap and seems very promising to prevent death among those that require oxygen/ventilator, IE, a severe case of covid-19. Steroid dexamethasone reduces deaths among patients with severe COVID-19 - trial shows 11 hrs ago Steroid dexamethasone reduces deaths among patients with...
  17. DragonBits

    Lowering Testosterone May Reduce Severity of COVID-19

    The science behind testosterone and COVID-19 May 28, 2020 A new study led by David Goldstein, PhD, director of the Institute for Genomic Medicine at Columbia University Irving Medical Center, and Xinchen Wang, PhD, a postdoctoral researcher at the institute, informed the idea to treat COVID-19...
  18. Vince

    Before Catching Coronavirus, Some People’s Immune Systems Are Already Primed to Fight It

    Some people's immune systems may have a head start in fighting the coronavirus, recent research suggested. A study published last month in the journal Cell showed that some people who have never been exposed to the coronavirus have helper T cells that are capable of recognising and responding...
  19. DragonBits

    Interesting article on covid vaccine effectiveness

    The world needs Covid-19 vaccines. It may also be overestimating their power. By HELEN BRANSWELL @HelenBranswellMAY 22, 2020 With a little luck and a lot of science, the world might in the not-too-distant future get vaccines against Covid-19. But those vaccines won’t necessarily prevent all...
  20. J

    Ingesting Semen No Cure for Covid-19

    A video has been viewed more than 100,000 times in multiple posts on YouTube, Facebook and Twitter in which a purported Philippine doctor claims ingesting semen could cure a patient infected with the novel coronavirus, citing a 2016 scientific study. The claim is false; the authors of the 2016...
  21. DragonBits

    people catch cold-causing coronaviruses twice in the same year

    What if immunity to covid-19 doesn’t last? (Some scientists find the question too dark to contemplate. ) Starting in the fall of 2016 and continuing into 2018, researchers at Columbia University in Manhattan began collecting nasal swabs from 191 children, teachers, and emergency workers...
  22. J

    Low T a Risk Factor for Covid-19

    A study evaluated the risk factors of men admitted to a hospital in Germany for Covid-19 and found that one factor is low testosterone levels. This run contrary to recent discussion in the media where it has been argued that testosterone raises the risk for Covid-19. The preprint is on MedRxiv...
  23. P

    Does Testosterone Make COVID-19 Worse?

    Interested to see thoughts here. I am still wondering about the high prevalence of COVID-19 in males. What is it? Lifestyle choices - smoking, alcohol use, the likelihood of other comorbidities, like high blood pressure, diabetes, obesity...
  24. J

    Vitamin D Protects Against Covid-19

    The paper says it is the first study to show that Vitamin D levels are associated with Covid-19 mortality. Currently I take 5000 IU of Vitamin D EOD and after reading this paper will step it up to every day. The abstract is at the link and the full paper can be downloaded as a pdf there. This...
  25. J

    Soy Phytoestrogens May Help Prevent Covid-19

    Computer simulations looked for natural compounds that bind to the coronavirus spike to prevent it from docking to cells. Estrogens and the phytoestrogens in soy were the best candidates. And no, soy phytoestrogens won't feminize you, their estrogenic activity is much weaker than estrogen. The...
  26. M

    Covid and blood clots - article suggests significant cause of mortality

    This is a non-medical site, but passing along for the collective brain trust to review. A mysterious blood-clotting complication is killing coronavirus patients
  27. P

    Doctors discover why severe coronavirus cases are more common in men

    Interesting read - ACE2 from Testicles Doctors discover why severe coronavirus cases are more common in men Actual Study Link https://www.medrxiv.org/content/10.1101/2020.04.16.20060566v1.full.pdf
  28. Nelson Vergel

    Vitamins to Prevent Coronavirus Infection?

    Dr. Seheult's daily regimen to optimize his immune system and minimize COVID-19 risk. In the absence of good clinical data that is specific to SARS-CoV-2, Dr. Seheult discusses supplements, sleep, and his daily disinfection routine when removing PPE, getting in his car, and returning home from...
  29. S

    Anyone Successfully Lower HCT by Reducing T Dose?

    My last blood test Hct came back at 53 back in March. Then this coronavirus hit and I haven't had a chance to recheck it. I am not having symptoms other than feeling very itchy. The last time I donated blood I had a very hard time. Felt lightheaded and short of breath for a day afterwords. I am...
  30. J

    Age and Obesity Biggest Risks for Covid-19

    A preprint of a new study identifies age (>= 65) and obesity (BMI > 40) the biggest risk factors observed in admissions in New York City. The abstract says: "We conducted a cross-sectional analysis of all patients with laboratory-confirmed Covid-19 treated at a single academic health system in...
  31. Vince

    Peter Attia has added an open page on his blog specifically on COVID-19

    Up-to-Date Coronavirus (SARS-CoV-2 / COVID-19) Information Currently, my entire clinical and research team are working on trying to make sense of the SARS-CoV-2 / COVID-19 pandemic. We’re constantly in contact with leading experts and doctors working on this issue around the world, and our goal...
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