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  1. Pacman

    What is the reason that nandrolone causes depression? (Mechanism of action)

    Nandrolone is literally the only thing (so far) that helps me manage shoulder pain due to my cervical radiculopathy. But even at low doses (~60 mg a week), I seem to get very depressed on it, and feel "flatlined" about life in general. Good news is that even at 60 mg it helps immensely. I've...
  2. Pacman

    Semaglutide for neuropathic pain? (link to study)

    I found this study that found a link between GLP-1 receptors and neuropathic pain: Microglial Activation of GLP-1R Signaling in Neuropathic Pain Promotes Gene Expression Adaption Involved in Inflammatory Responses This is the only study I have found on this topic (so far), but if that study's...
  3. Pacman

    Very basic question regarding how to adjust AI dosages based on T dosages

    I been on TRT for 10 years at this point. I find that my current default "sweet spot" (as far feeling good and having a fairly high sex drive and function) revolves around the 100-130 mg T cyp every 3 days with no AI. Occasionally though I like to experiment with different dosages (in both...
  4. Pacman

    What are all these steroid info sites that also offer "legal alternatives" to steroids?

    Here are two examples: Site 1 - Anabolic Steroids: types, uses and risks | Steroid .com Site 2 - https://insidebodybuilding.com/anavar-results-before-after The info on the sites themselves appears to be very accurate. But then they have ads for these obvious BS legal alternatives. There are...
  5. Pacman

    What are your experiences on modafinil?

    I have searched the forum for this topic, and I have seen modafinil being discussed in the past, but I have not found any recent discussions about modafinil specifically. My issue: I often have issues with getting fatigued fairly often. I get tired early and my focus very frequently goes out...
  6. Pacman

    For peptides that need refrigeration, what is the solution for for extended power outages?

    Basically the title. I was just thinking about this as hurricane Ian pummeled through Florida, and apparently 2 million are stuck without electricity. Some of these power outages could last a day, some of them could last last over a week in some areas. (In Florida specifically I doubt that...
  7. Pacman

    What is the timeline of how quick injectables and AIs affect us?

    For example, if I wanted to see if taking an AI would help with moodiness with my T shots, is it best to take an AI the same day, the day after, the day before? (Would it be better to use it as a "preventative" blocker?) Once you inject testosterone cypionate, do your T levels (and by...
  8. Pacman

    Semaglutide: Preventing/Dealing with Side Effects

    Hi all! I just received my Semaglutide medicine. I am planning to take it later today for the first time. I am excited about it (due to the fact that I have always had weight issues my entire life) but also very nervous (because I tend to have GI issues easily, usually in the form of...
  9. Pacman

    3rd party testing of peptides and incurred costs?

    Where would one send their vial of peptides to get tested analyzed? I do like the fact that certain sites do publish COAs, but I feel it would be safe to assume that unless we do random 3rd party tests ourselves, there's no real way to verify 100% that what they sell is legit and pure, and that...
  10. Pacman

    Does nandrolone contribute to (or cause) depression?

    I added nandrolone officially to my regimen about one month ago (I have tried it in the past but never very long). The purpose of adding it was to assist in resolving joint pain, and it works PERFECT!! 10 out 10, joint pain is nearly non-existent! I am doing physical therapy in addition...
  11. Pacman

    Has anyone here tried HIMS topical spray along with their shampoo? What results did you get?

    I am thinking of trying out their combo spray (0.3% finasteride + 6% minoxodil). I have a receding hairline and general thinning hair. Has anyone tried their spray and/or their shampoo? How are the results? And how long did it take before you started seeing results? This is the spray...
  12. Pacman

    Odd side effect from testosterone - eczema?

    So this is a bit of a weird side effect that I attribute to testosterone. So I have had recurring eczema on my hands (on and off, and always much worse in the winter) since I was a teen. In the last 5-6 years it got even worse and more frequent. I often can't go more than 2 days without...
  13. Pacman

    Just had the biggest scare of my life (PSA = 10.6)!! Need some advice.

    In 6 months my total PSA went from 1.4 ng/dL to 10.6 ng/dL! This freaked me out like crazy, especially since my dad passed away two years ago from prostate cancer and that was literally the exact way he found out that he had prostate cancer. I am in my 30s. So a jump that high in just 6...
  14. Pacman

    Osteoarthritis and adding nandrolone to TRT

    I have osteoarthitis in my shoulder. I have tried PRP ($1500), physical therapy ($1200), I modified several upper body exercises to work the muscles without heavily inflaming the current state of my shoulder (I get creative), I focus a ton on joint health (CARs, etc), and have found very...
  15. Pacman

    I think I may have found a method of controlling sex drive on TRT.

    This is merely my inconclusive hypothesis based on my experience in the last month when I started increasing AI doses to find my "sweet spot". If I could actually control my sex drive in such a predictable manner, that would be insanely amazing!! I have found that my sex drive largely depends...
  16. Pacman

    What are your experiences with PT-141? (as an aphrodisiac)

    I found this thread submitted by @Nelson Vergel : PT 141 forum But it is only general information. Does anyone here use PT-141 for assistance with arousal? How has it been? I just got approved for this treatment since I have been disinterested in sex recently... (I haven't felt the need to...
  17. Pacman

    Finding the right AI dosage

    So long story short, I have been for years without an AI. When I started taking them (1-2 a week @ 0.125 mg/pill) my sex drive got better. I had no idea I had an issue to begin with even with the blood tests with high estradiol due to the fact that I thought I felt fine (and my doctor said...
  18. Pacman

    Do androgen receptors become desensitized over time with TRT?

    I was told this by somebody a while ago. Is this true? And if it is, does that mean over time an increased dose is needed to achieve the same results? The person who told me this said the only way to "re-sensitize" them is to completely stop injections for 2-3 months. I don't know how I feel...
  19. Pacman

    How long after the "best use date" (BUD) does T cyp/prop retain its full efficacy?

    Let's say it is unopened, in a closed box not near sunlight, at room temperature. Is there a certain point it tends to get "weaker"? One year after the BUD? Two years after? Right away? Same question regarding AIs. Any data in regards to AIs as well?
  20. Pacman

    Restoring penile sensitivity

    I am having trouble with sensitivity in my penis (it is not sexually sensitive at all), and recently when I had sex it was VERY difficult to maintain an erection with a condom on. I was only able to maintain it with no condom, and even then I had some issues... So I am posting this thread...
  21. Pacman

    Different reactions to different esters?

    Is it possible that one's body does not react the same to cypionate, propionate, enanthate? I mean it is all the same hormone, so why would it be different? Did it ever happen to anyone where you inject similar protocols between similar esters (say 200 mg weekly cypionate and then start with...
  22. Pacman

    How long after the T injection are T levels the highest?

    I am asking about all three most common esters: cypionate, enanthate, propionate; because I know that the peak happens all at different times post-inection for all three of those... Generally speaking, I always do blood tests when my T levels are lowest (the day of my injection before I inject)...
  23. Pacman

    Are there independent labs that can verify the purity and potency of my prescriptions?

    Just something I want to do every once in a while, because I occasionally have that little bug in my head. I know it's probably a waste of money, but I want to do it anyway. What kind of services exist out there that offer this? How long does it take and do they respect privacy? And do they...
  24. Pacman

    Injection leakage

    I inject in the ventro glute 2-4 times a week (depending how I split up my weekly dose). I often have a stream of the oil drip down my leg right after I pull the needle out. I tried the z-track and 90 degree angle method as I read on another source of the internet and it doesn't always work...
  25. Pacman

    Does it matter whether or not I inject in the same muscle every time?

    I inject twice weekly, sometimes more if I divide it up into smaller doses. Is there any sense in purposely injecting in different muscles, other than simple soreness? More effective one way or another?
  26. Pacman

    Is there any way to reverse balding? Anybody have success?

    I am 29, and I noticed about one month ago my hair was starting to thin and the there was a noticeable amount of skin exposed where hair was right above my temples. Basically temporal recession. This is driving me nuts, because I always had a very thick head of hair. I went to a...
  27. Pacman

    My HCG vial was out of fridge for almost 5 days, can I still use it?

    I live in the path of Irma, so I had to evacuate, and there were no flight by the time I had to leave so I had to drive away. Trip was about 3 days and the vial was out of the fridge the whole time, but never in direct sunlight and never in extreme heat. Is it still good? Should I throw it away?
  28. Pacman

    Applying Topi-Click T gel to the scrotum - a few questions

    1) After about an hour or two, the gel leaves a "cake" texture on my scrotum. Is this normal? 2) When applying a few clicks, does some of the absorption get blocked by applying "too much"? (occasionally I skip 2-3 days application and apply 2-3 days worth at once) 3) Is it recommended to...
  29. Pacman

    Got a script for T cream w/ Topi-Click - couple questions.

    I have a prescription with one of those 'click' dispensers, and for each application I need to dispense one click. However whenever I do that click, only a tiny amount of cream comes out, and it seems like it is dispensing a lot less than it should. The concentration is 200 MG/GM (20%), and...
  30. Pacman

    What is the timeline of peak T levels per method of administration?

    I was wondering how long it takes the T levels to peak. Like if I inject 1 cc cypionate, do my levels reach the peak right after, or a day or two after from that specific injection? Same question for propionate and topicals...
  31. Pacman

    Checking for gyno - how do you know if it's happening?

    A few weeks ago, my nipples got really itchy and I scratched the hell out of them and they were very sore the next day. Ever since about then my nipples were noticeable puffier and basically hard and protruding 90% of the time. I do not have any noticeable soreness and the itching is every so...
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