My experience differs from yours in this regard. Daily propionate was giving me a little more variation than what's natural even for young guys, so I'm replacing part of the dose with enanthate. The pharmacokinetics of topical testosterone are also dependent on the formulation and the individual. Some published response curves are quite flat, meaning diurnal variation is not assured. Additionally, in natural males testosterone is rising significantly in the early morning hours. In theory this would be easier to emulate with propionate injections, though I find testosterone injections at bedtime interfere with sleep.... To answer one of your questions, injectable modalities in no way whatsoever mimics human physiology, even with daily injections. I did propionate a few weeks and my levels were sky high three days after a single injection. Topicals are the closet in mimicking our natural processes. You’re not supposed to have elevated t around the clock. This is one of the problems that causes insomnia in a lot of men. ...
Ya, I’d have to agree. 300mg/ day isn’t crazy high. It is around the top end for dosing though. But again, 300mg/ day seems to be around the top end for guys doing all of it on the scrotum.
How does this work out in terms of cost and logistics as empower only has the 20% 30mL clickers. Do you have to order 2 of those at a time or do you order 1 clicker but more frequently than once a month ? Or is it a larger clicker ?
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038