Excel Male Health Forum

The Leading Men's Health Forum for Testosterone Optimization & Hormone Wellness

Welcome to ExcelMale.com — the most trusted, expert-moderated community for men seeking evidence-based guidance on testosterone replacement therapy (TRT), hormone optimization, and total wellness. Since 2010, we've helped thousands of men take control of their health.

24,000+ Active Members
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20+ Years Expert Experience

Why ExcelMale? Evidence-Based Men's Health Information You Can Trust

Navigating testosterone replacement therapy and hormone health can be overwhelming. Conflicting information, outdated medical advice, and unqualified opinions flood the internet. ExcelMale.com was created to cut through the noise — providing a rigorously moderated space where men share real experiences, backed by clinical research and guided by genuine expertise.

Whether you're exploring TRT for the first time, optimizing your current protocol, managing side effects like elevated hematocrit or estradiol, or seeking to preserve fertility with HCG therapy, our community offers the knowledge and support you need. We discuss everything from injection frequency and bloodwork interpretation to lifestyle factors that affect testosterone levels.

"I founded ExcelMale after decades of personal experience with hormone optimization and seeing how difficult it was for men to find reliable, science-based information. Every man deserves access to knowledge that can transform his quality of life."

— Nelson Vergel, Founder & Author of Testosterone: A Man's Guide

Nelson Vergel has spent four decades turning personal health challenges into a mission that's helped thousands of men reclaim their vitality. Diagnosed with HIV in 1985 and then creating a testosterone-based program to reverse wasting syndrome for himself and his peers, he became a pioneer in understanding how hormones affect quality of life—and has been on TRT himself for over 30 years.

A chemical engineer by training, Nelson has served as a key opinion leader for pharmaceutical companies on clinical research strategy, trained clinicians on hormone optimization protocols, and authored definitive guides including Testosterone: A Man's Guide & Beyond Testosterone. He founded DiscountedLabs.com to make lab testing accessible and built ExcelMale.com into a community where men find and share evidence-based answers.

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Is Metformin a Miracle Drug ? : Nelson Vergel Explains
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Jay Campbell invited me to present a review of relevant data on the use of Metformin in men with and without diabetes. I hope you enjoy the work I put into explaining the data to clarify the myths and facts about this old drug that is creating...
FDA Rejects Test E Autoinjector, Xyosted
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The news article says: Antares Pharma had applied for approval of the product for men with physician-determined hypogonadism. The prefilled, single-use injector enables patients to self-administer testosterone at home instead of applying a...

Many Men Have Low Adherence to Topical Testosterone

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This news article on a talk at the American Association of Clinical Endocrinologists 2017 Conference surprised me Low adherence in men using testosterone gels Fewer than one in five hypogonadal men are adherent to prescribed topical...

NSAIDs Associated With Higher Testosterone Levels

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It's well established that opiates, over time, can suppress male androgen levels, leading to hypogonadism. Danish researchers recently examined the question of non-prescription analgesics and the relationship they had to male reproductive...
Metformin and PSA Levels: Does it Make a Difference?
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Metformin, the first-line antihyperglycemic, has been touted as something of a wonder drug with strong, anti-aging properties. A recent study conducted in Toronto was undertaken to determine if Metformin administration had any impact on PSA...

A Review of Testosterone Heart Attacks Based on Prescription Data

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Another paper in the Asian Review of Andrology reviews the studies of cardiovascular events that were based on analyzing prescription records. Each study is summarized and its weaknesses discussed. The conclusion is that most studies have found...

Fluoride Exposure Increases Estradiol Levels in Men

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New evidence suggests that fluoride may be an sexual hormone disruptor. From the abstract: We conducted a cross-sectional study in rural areas of Henan province in China to explore the interaction between the estrogen receptor alpha...

Waist Circumference: The Best Metric for Predicting Sexual Symptoms for Hypogonadal Men

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It's been well established that waist circumference is a useful, reliable predictor for cardiovascular risk. However, until earlier this year it was not certain what its value was in regard to sexual health/quality of life status in hypogonadal...

Testosterone and Stroke: No Connection Found, But More Research Called For

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While there have been studies of the role TRT may play in terms of cardiovascular disease, there have been few focusing specifically on TRT and stroke. Testosterone Replacement Therapy and the Risk of Stroke in Men: A Systematic Review...
Kidney Function: Cystatin C vs. Creatinine in Determining Risk
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Does adding the measurement of cystatin C to that of serum creatinine to determine estimated glomerular filtration rate improve its accuracy? That's the question asked by researchers who undertook a meta-analysis of 11 general population studies...

DHEA Levels Are Associated With Lower Risk of Type II Diabetes

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A recent study published in Diabetologiainvestigated the impact of DHEA, DHEAS, androstenedione, and the ratio of DHEAS to DHEA on type II diabetes. Data from 5,189 men and women were gathered. After adjusting for age, sex, cohort, fasting...
Sperm counts significantly declining in men from North America, Europe
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BACKGROUND Reported declines in sperm counts remain controversial today and recent trends are unknown. A definitive meta-analysis is critical given the predictive value of sperm count for fertility, morbidity and mortality...

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