ExcelMale Forum. TRT, Hormones, Peptides, Men’s Health

The Leading Men's Health Forum for Testosterone Optimization & Hormone Wellness

Welcome to ExcelMale.com — the most trusted, expert-moderated community for men seeking evidence-based guidance on testosterone replacement therapy (TRT), hormone optimization, and total wellness. Since 2010, we've helped thousands of men take control of their health.

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Why ExcelMale? Evidence-Based Men's Health Information You Can Trust

Navigating testosterone replacement therapy and hormone health can be overwhelming. Conflicting information, outdated medical advice, and unqualified opinions flood the internet. ExcelMale.com was created to cut through the noise — providing a rigorously moderated space where men share real experiences, backed by clinical research and guided by genuine expertise.

Whether you're exploring TRT for the first time, optimizing your current protocol, managing side effects like elevated hematocrit or estradiol, or seeking to preserve fertility with HCG therapy, our community offers the knowledge and support you need. We discuss everything from injection frequency and bloodwork interpretation to lifestyle factors that affect testosterone levels.

"I founded ExcelMale after decades of personal experience with hormone optimization and seeing how difficult it was for men to find reliable, science-based information. Every man deserves access to knowledge that can transform his quality of life."

— Nelson Vergel, Founder & Author of Testosterone: A Man's Guide

Nelson Vergel has spent four decades turning personal health challenges into a mission that's helped thousands of men reclaim their vitality. Diagnosed with HIV in 1985 and then creating a testosterone-based program to reverse wasting syndrome for himself and his peers, he became a pioneer in understanding how hormones affect quality of life—and has been on TRT himself for over 30 years.

A chemical engineer by training, Nelson has served as a key opinion leader for pharmaceutical companies on clinical research strategy, trained clinicians on hormone optimization protocols, and authored definitive guides including Testosterone: A Man's Guide & Beyond Testosterone. He founded DiscountedLabs.com to make lab testing accessible and built ExcelMale.com into a community where men find and share evidence-based answers.

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Interaction Between a Daily Dosed Tadalafil, Dosazoxin and Tamsulosin

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Abstract The hemodynamic interaction between tadalafil (5 mg/d) and doxazosin or tamsulosin was investigated in 2 randomized, double-blind, crossover phase 1 studies. Healthy men (n = 45) received tadalafil or placebo for 28 days and...

Psychiatric Manifestations of Endocrine Disorders

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Review Article Psychiatric Manifestations of Endocrine Disorders Full Paper: http://www.heraldopenaccess.us/fulltext/Human-Endocrinology/Psychiatric-Manifestations-of-Endocrine-Disorders.php#tab2 ADRENAL: CUSHING’S SYNDROME...

Testosterone Replacement Reduces Risk of Atrial Fibrillation

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Another study showing TRT reduces the risk of heart disease. Full text of the journal article is available. Atrial fibrillation (AF) is the most common cardiac dysrhythmia associated with significant morbidity and mortality. Several small...

Article on Steroid Use and Testosterone

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Reason Magazine has an article on steroid use in America, called How Washington Lost the War on Muscle. It also covers testosterone replacement therapy at length, with quotes from Dr. Morgentaler. Since it's a libertarian magazine, their position...

A Review of Studies of Testosterone's Adverse Cardiovascular Effects

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This review (full text) discusses the studies and meta-analyses of adverse cardiovascular events from testosterone replacement therapy. Their conclusion is that no firm conclusion can be gathered from the studies to date. In summary, the...

A Review of Testosterone CV Studies Based on Prescription Data

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Another paper in the Asian Review of Andrology reviews the studies of cardiovascular events that were based on analyzing prescription records. Each study is summarized and its weaknesses discussed. The conclusion is that most studies have found...
Nelson Vergel's Top 10 Testosterone Commandments
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1.Have reasonable expectations. Testosterone is not a magic bullet. 2.Do not fall prey to testosterone booster scams. 3.Do not obsess about estradiol without testing it with right (sensitive) test. 4.Monitor your...
Is DHT the Cause of BPH ( Prostate Enlargement ) or is it Estradiol?
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I keep reading posts that say DHT isn't the cause of BPH, estrogen is the cause. if thats the case then why do drugs like finasteride which lower dht actually shrink the prostate? if it was estrogen then taking finasteride would never shrink...

Video: A Guy's Guide to Maintaining Sexual Health by Dr Turek

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Excellent lecture. Dr. Paul Turek, an international thought leader on men's health issues, will present an overview of sexual health for men at any age. This talk will address the concepts and cures for common sexual issues such as low sex...

Perrigo Announces FDA Final Approval For Generic Version Of Androgel

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Perrigo Company plc (NYSE; TASE: PRGO) today announced it has received final approval from the U.S. Food and Drug Administration for its AB rated Abbreviated New Drug Application referencing AbbVie Inc.'s Androgel® Topical Gel, 1.62% packets...
Men with high levels of anabolic hormones less likely to develop worsening frailty
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The researchers found that having higher baseline levels of vitamin D, insulin-like growth factor-1 (IGF-1) and its binding protein 3 (IGFBP3) was associated with a lower risk of worse frailty status four years later. "Vitamin D, besides...
Decreased testosterone, DHT and estradiol were associated with higher mortality in men.
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Temporal Changes in Androgens and Estrogens Are Associated With All-Cause and Cause-Specific Mortality in Older Men. Hsu B, et al. J Clin Endocrinol Metab. 2016. Abstract CONTEXT: The dynamic temporal relationship between changes in...

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