Excel Male Health Forum

The Leading Men's Health Forum for Testosterone Optimization & Hormone Wellness

Welcome to ExcelMale.com — the most trusted, expert-moderated community for men seeking evidence-based guidance on testosterone replacement therapy (TRT), hormone optimization, and total wellness. Since 2010, we've helped thousands of men take control of their health.

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Why ExcelMale? Evidence-Based Men's Health Information You Can Trust

Navigating testosterone replacement therapy and hormone health can be overwhelming. Conflicting information, outdated medical advice, and unqualified opinions flood the internet. ExcelMale.com was created to cut through the noise — providing a rigorously moderated space where men share real experiences, backed by clinical research and guided by genuine expertise.

Whether you're exploring TRT for the first time, optimizing your current protocol, managing side effects like elevated hematocrit or estradiol, or seeking to preserve fertility with HCG therapy, our community offers the knowledge and support you need. We discuss everything from injection frequency and bloodwork interpretation to lifestyle factors that affect testosterone levels.

"I founded ExcelMale after decades of personal experience with hormone optimization and seeing how difficult it was for men to find reliable, science-based information. Every man deserves access to knowledge that can transform his quality of life."

— Nelson Vergel, Founder & Author of Testosterone: A Man's Guide

Nelson Vergel brings over 20 years of clinical research experience, having worked with major pharmaceutical companies and authored definitive guides on testosterone therapy. As founder of DiscountedLabs.com and a recognized expert in men's health advocacy, Nelson ensures every discussion on ExcelMale meets the highest standards of accuracy and usefulness.

Ready to Optimize Your Health?

Join thousands of men who have transformed their lives through evidence-based hormone optimization. Ask questions, share experiences, and learn from experts.

Perrigo Announces FDA Final Approval For Generic Version Of Androgel

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Perrigo Company plc (NYSE; TASE: PRGO) today announced it has received final approval from the U.S. Food and Drug Administration for its AB rated Abbreviated New Drug Application referencing AbbVie Inc.'s Androgel® Topical Gel, 1.62% packets...
Men with high levels of anabolic hormones less likely to develop worsening frailty
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The researchers found that having higher baseline levels of vitamin D, insulin-like growth factor-1 (IGF-1) and its binding protein 3 (IGFBP3) was associated with a lower risk of worse frailty status four years later. "Vitamin D, besides...
Decreased testosterone, DHT and estradiol were associated with higher mortality in men.
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Temporal Changes in Androgens and Estrogens Are Associated With All-Cause and Cause-Specific Mortality in Older Men. Hsu B, et al. J Clin Endocrinol Metab. 2016. Abstract CONTEXT: The dynamic temporal relationship between changes in...

Influence of IGF-1, DHEA and DHT on acne

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Arch Dermatol. 2005 Mar;141(3):333-8. Correlation between serum levels of insulin-like growth factor 1, dehydroepiandrosterone sulfate, and dihydrotestosterone and acne lesion counts in adult women. Abstract OBJECTIVES: To...

Testosterone Gel Adherence Low Among Hypogonadal Men

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Fewer than one in five hypogonadal men are adherent to prescribed topical testosterone, new research indicates. The findings, from a large commercial insurance database, were presented May 5 here at the American Association of Clinical...

NY State Testosterone and HCG Prescribing Requirements

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Question from doctor: Can I use EMPOWER pharmacy in Houston to get testosterone to someone in NYC legally? For some reason there you need a prescription monthly as they don't allow refills and it is quite cumbersome to the patient...
No Link Between Testosterone Levels and Male Pattern Baldness
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A recent study failed to find a link between testosterone levels and male pattern baldness: A cross-sectional population study conducted in Northeastern Germany examined 373 men from the general population who had not received prescribed...

Testosterone Replacement Enhances the Effects of Metformin on Lipids and Inflammation

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Exp Clin Endocrinol Diabetes 2015; 123(10): 608-613 The Effect of Metformin and Metformin-Testosterone Combination on Cardiometabolic Risk Factors in Men with Late-onset Hypogonadism and Impaired Glucose Tolerance Abstract No...

Testosterone Reduces Fat by Decreasing Leptin Resistance

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“The novelty in our study stems from the fact that we simultaneously investigated the effects of testosterone in the context of a rigorous weight-loss program,”Mathis Grossmann,MD,PhD,FRACP,professor in the department of medicine at the...
Exposure to Phthalates Decreases Testosterone and Sperm Quality in Men
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Phthalates are used in a large variety of products, from enteric coatings of pharmaceutical tablets and nutritional supplements to viscosity control agents, gelling agents, film formers, stabilizers,dispersants, lubricants, binders, emulsifying...
Research Options for Erectile Dysfunction: Stem Cells and More
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The best paper to date summarizing research therapies for ED. I highly recommend reading the full paper below (attached file- Register on ExcelMale to open it). Abstract: Although oral phosphodiesterase-5 (PDE5) inhibitors are...
Water Retention Caused by Testosterone May Have Nothing to Do with Estradiol
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I get a lot of emails from men on testosterone replacement therapy (and/or HCG) that feel they have water retention (some with ankle swelling) and they are puzzled that their estradiol is low or below 35 micrograms/ml. They may have tried...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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