Excel Male Health Forum

The 11 Year-Old Study That Proves Testosterone Injections Every Two Weeks Fail

Nov 30

We still regularly have members join us who have been prescribed an injection of testosterone, 200mg, every two weeks. New to the TRT game the member, in all good-faith, wonders why he feels even worse than he did prior to the start of hormone...

Coffee May Increase SHBG

Nov 30

I'm quoting the abstract, but it seems a rather weak result. 1,410 men aged 20 + years who attended the morning examination session of the Third National Health and Nutrition Examination Survey (1988–1991) were included in the...

Magic Mushrooms For Depression?

Nov 20

In a small study at the Imperial College of London, 19 patients received a single dose of the psychedelic psilocybin. All had been diagnosed with, and were suffering from, depression that had been resistant to treatment. Twenty four hours after...

Treating Low Sexual Desire in the Post-Menopausal Woman

Nov 20

At the present tine. flibanserin (Addyi, Valeant Pharmaceuticals) is the only approved therapy for hypoactive sexual desire disorder in women. However, it is only indicated for use in premenopausal women. According to Dr. Sheryl Kingsberg...

Needle-Free Injections For ED: Do the Devices Work?

Nov 20

Needle phobia is a well recognized phenomenon that it is believed affects 10% of the population. In the diabetic population, that number jumps to nearly 80%. Fear of needles is believed to be the single largest reason that many diabetics are not...

Low Serum Testosterone in Outpatient Psych Clinics

Nov 20

In a study that confirmed what seems so obvious to members of Excelmale, researchers have concluded that there is: "a lack of information on the prevalence of low testosterone in patients presenting with psychiatric complaints despite an...

Review of Studies of Testosterone to Assess Stroke Risk

Nov 20

Although two of seven studies showed reduced stroke risk, the review could not come to a definitive conclusion. Among eight RCTs, a low frequency of stroke events (<5) was observed across both testosterone and control groups, thus...

Is Metformin a Miracle Drug ? : Nelson Vergel Explains

Nov 08

Jay Campbell invited me to present a review of relevant data on the use of Metformin in men with and without diabetes. I hope you enjoy the work I put into explaining the data to clarify the myths and facts about this old drug that is creating...

FDA Rejects Test E Autoinjector, Xyosted

Oct 23

The news article says: Antares Pharma had applied for approval of the product for men with physician-determined hypogonadism. The prefilled, single-use injector enables patients to self-administer testosterone at home instead of applying a...

Many Men Have Low Adherence to Topical Testosterone

Sep 22

This news article on a talk at the American Association of Clinical Endocrinologists 2017 Conference surprised me Low adherence in men using testosterone gels Fewer than one in five hypogonadal men are adherent to prescribed topical...

NSAIDs Associated With Higher Testosterone Levels

Sep 22

It's well established that opiates, over time, can suppress male androgen levels, leading to hypogonadism. Danish researchers recently examined the question of non-prescription analgesics and the relationship they had to male reproductive...

Metformin and PSA Levels: Does it Make a Difference?

Sep 22

Metformin, the first-line antihyperglycemic, has been touted as something of a wonder drug with strong, anti-aging properties. A recent study conducted in Toronto was undertaken to determine if Metformin administration had any impact on PSA...

TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038