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The Leading Men's Health Forum for Testosterone Optimization & Hormone Wellness

Welcome to ExcelMale.com — the most trusted, expert-moderated community for men seeking evidence-based guidance on testosterone replacement therapy (TRT), hormone optimization, and total wellness. Since 2010, we've helped thousands of men take control of their health.

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Navigating testosterone replacement therapy and hormone health can be overwhelming. Conflicting information, outdated medical advice, and unqualified opinions flood the internet. ExcelMale.com was created to cut through the noise — providing a rigorously moderated space where men share real experiences, backed by clinical research and guided by genuine expertise.

Whether you're exploring TRT for the first time, optimizing your current protocol, managing side effects like elevated hematocrit or estradiol, or seeking to preserve fertility with HCG therapy, our community offers the knowledge and support you need. We discuss everything from injection frequency and bloodwork interpretation to lifestyle factors that affect testosterone levels.

"I founded ExcelMale after decades of personal experience with hormone optimization and seeing how difficult it was for men to find reliable, science-based information. Every man deserves access to knowledge that can transform his quality of life."

— Nelson Vergel, Founder & Author of Testosterone: A Man's Guide

Nelson Vergel brings over 20 years of clinical research experience, having worked with major pharmaceutical companies and authored definitive guides on testosterone therapy. As founder of DiscountedLabs.com and a recognized expert in men's health advocacy, Nelson ensures every discussion on ExcelMale meets the highest standards of accuracy and usefulness.

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Liquid Chromatography/Mass Spectrometry is More Accurate for Hormone Blood Testing Than Older IAs

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Table of Contents Roli L, et al. J Endocrinol Invest. 2017. The steroid response to human chorionic gonadotropin (hCG) stimulation in men with Klinefelter syndrome does not change using immunoassay or mass spectrometry. Abstract Purpose...
Low Testosterone Causes and Benefits of Treatment
Men’s Heart Disease Partly Due to Low Estrogen
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The study was presented at the Endocrine Society's 97th annual meeting this month. In addition to finding that higher levels of testosterone led to lower HDL, and that estrogen didn’t affect HDL, Yu’s team found that low levels of estrogen led to...
Clinical Aspects of Gynecomastia in Adult Males: A Multicenter Study
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Table of Contents Clinical and Etiological Aspects of Gynecomastia in Adult Males: A Multicenter Study Gynecomastia, defined as the benign proliferation of breast glands in males, is a common complaint that produces anxiety and discomfort...
Case Report: HCG Restores Spermatogenesis
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The questions are regularly posed here at Excelmale: Will HCG help me maintain fertility while on a TRT protocol? How much HCG must I use to remain fertile? This Case Report Answers Some of Those Questions A 40 year old man presented to an...
Fasting May Regenerate/Repair Intestinal Stem Cells
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It's a mouse study - the point is acknowledged. However, new research at MIT raises some intriguing issues. As people age, their intestinal stem cells begin to lose their ability to regenerate. These stem cells are the source for all new...
Viagra or Placebo: Surprising Results From a New Study
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Table of Contents It's been known for years that PDE5 inhibitors, Viagra, Cialis, Levitra, improve erectile function in men. However, a surprising number of men in a double-blind, controlled study of sildenafil (Viagra) responded well -...
New Testosterone Natesto Data- Interview with Dr Ramasamy- Part 3
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Interview Transcript - Part 3 of 3 Read Part 1 Read Part 2 Nelson Vergel:                  And could we go real quick on describing what the numbers below mean? Is that ...? Dr Ramasamy:                   Sure. Basically, the number of...
New Testosterone Natesto Data- Interview with Dr Ramasamy- Part 2
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Interview Transcript- Part 2 of 3 Read Part 1 here Dr Ramasamy:                   So what is Natesto? Dr Ramasamy:                   Natesto is a nasal testosterone. It delivers 11mg of testosterone per pump per nostril and it's used three...
New Testosterone Nasal Gel (Natesto) Data- Interview with Dr Ramasamy
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Interview Transcript : Part 1 of 3 Nelson Vergel:                  Hello everybody, Nelson Vergel here with ExcelMale.com and DiscountedLabs.com. I'm very happy here to have Dr. Ramasamy, we've done a webinar before, on estradiol and...
How to Lower SHBG and Increase Free Testosterone
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Table of Contents A regular total testosterone blood test shows you how much of this male sex hormone is circulating through your bloodstream. However, this is just part of the whole picture. There are other hormones involved that could...
Estradiol In Men – Why Is It Important For Optimal Health And Fitness Performance – Part 1
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Table of Contents Estradiol is the most important female sex hormone and it plays a significant role in developing female secondary sexual characteristics. It also plays a vital role in maintaining proper bone density, regulating body fat...

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