Curated By Nelson Vergel | ExcelMale.com | Updated February 2026 1. Introduction: The Critical Intersection of Sleep and Hormonal Health Are you meticulously optimizing your testosterone levels and nutrition, yet still struggling with daytime...
I have not had very good experiences with GLP-1 drugs. The appetite suppression was nice, but the gastrointestinal side effects were a deal breaker. Semaglutide and Tirzepatide both shut down my digestive system. My wife has been on Retatrutide...
The Angiotensin Tiebreaker: Choosing the Blood Pressure Med That Defends Your Brain 1. The Hook: More Than Just a Number Hypertension is often called the "silent killer," a leading modifiable risk factor for dementia that currently affects nearly...
Palmitoylethanolamide (PEA) A Comprehensive Review of Mechanisms, Clinical Evidence, and Practical Applications January 2026 Abstract Palmitoylethanolamide (PEA) is an endogenous fatty acid amide belonging to the N-acylethanolamine family with...
Great news today FDA Updates Hormone Therapy Labels: A Significant Shift in Menopausal Treatment Guidance In a major policy reversal announced today, the FDA has approved updated labeling for six menopausal hormone therapy (HRT) products...
Prepared: January 2026, Curated by Nelson Vergel Key Finding: Evolocumab induces significant coronary plaque regression and stabilization but does not differentially affect coronary calcium accumulation compared to statin monotherapy. However...
Dear ExcelMale Members, I'm reaching out to you today with a request that's deeply personal to me and I believe to many of you as well. As some of you know, compounded medications literally saved my life. In the early days of the AIDS crisis...
Executive Summary The Metformin to Augment Strength Training Effective Response in Seniors (MASTERS) trial was a randomized, double-blind, placebo-controlled multicenter study designed to determine if metformin could enhance the muscle-building...
When GLP-1 therapies hit the mainstream, testosterone health changed too. Now three new medications in FDA review could reshape the landscape again–not just for weight loss, but for how metabolic dysfunction relates to hormone balance in men...
I am highlighting this opportunity to ask you to submit a public comment in support of TRT de-scheduling by 2/9/2026. Click here to add your comment: Federal Register :: Request Access Key Points to Include in Public Comments: When submitting...
The Battle for Compounded GLP-1 Access: Regulatory Pressure, Litigation, and Affordability Executive Summary As of January 2026, the market for compounded GLP-1 receptor agonists—specifically semaglutide and tirzepatide—is at a volatile...
Testosterone Therapy in Pre- and Post-Menopausal Women Testosterone Therapy for Women: Indications and Evidence (2010–2025) Low Sexual Desire (HSDD) and Sexual Function Evidence: Multiple randomized controlled studies (RCTs) and meta-analyses...