Dear ExcelMale Members, I'm reaching out to you today with a request that's deeply personal to me and I believe to many of you as well. As some of you know, compounded medications literally saved my life. In the early days of the AIDS crisis...
Executive Summary The Metformin to Augment Strength Training Effective Response in Seniors (MASTERS) trial was a randomized, double-blind, placebo-controlled multicenter study designed to determine if metformin could enhance the muscle-building...
When GLP-1 therapies hit the mainstream, testosterone health changed too. Now three new medications in FDA review could reshape the landscape again–not just for weight loss, but for how metabolic dysfunction relates to hormone balance in men...
I am highlighting this opportunity to ask you to submit a public comment in support of TRT de-scheduling by 2/9/2026. Click here to add your comment: Federal Register :: Request Access Key Points to Include in Public Comments: When submitting...
The Battle for Compounded GLP-1 Access: Regulatory Pressure, Litigation, and Affordability Executive Summary As of January 2026, the market for compounded GLP-1 receptor agonists—specifically semaglutide and tirzepatide—is at a volatile...
Testosterone Therapy in Pre- and Post-Menopausal Women Testosterone Therapy for Women: Indications and Evidence (2010–2025) Low Sexual Desire (HSDD) and Sexual Function Evidence: Multiple randomized controlled studies (RCTs) and meta-analyses...
Why is that some people can sleep through the night while others toss and turn? No matter how early or late you get to bed, you can't seem to get a full night of rest? You've tried just about everything to improve your sleep--sleeping pills...
DEEP DIVE: Strategies to Increase Allopregnanolone A Comprehensive Review for Mental Health Support 1. What is Allopregnanolone? Allopregnanolone (ALLO) is a neurosteroid synthesized from progesterone that acts as a potent positive allosteric...
What You Need to Know Scientists have discovered that the trillions of bacteria living in your gut don't just help you digest food—they also control how much testosterone your body has available to use. They're calling this system the...
The psychedelic drug development landscape has reached an inflection point in early 2026, with Compass Pathways achieving the first positive Phase 3 psilocybin trial results in June 2025, while Lykos Therapeutics' MDMA rejection has reshaped...
Could a single weekly injection deliver unprecedented weight loss while preserving muscle mass and improving cardiovascular health? For men on testosterone replacement therapy (TRT) struggling with stubborn body fat despite optimized hormone...
If you've ever tried to figure out the right way to use protein for muscle growth, you've likely been buried under an avalanche of conflicting advice. From gym bro-science and supplement marketing to well-meaning but outdated tips, the noise can...