estrogen in men

U-Shaped Association Between Testosterone and Fractures
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The occurence of fractures in an elderly population is a significant concern, so this study looked at the relation between the number of fractures and hormone levels, including testosterone. It found fractures were higher at both low and high...
Estrogen-It's what makes a real man
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Study: Low estrogen can cause problems for men Study: Low estrogen can cause problems for men (2013) Dr. Joel Finkelstein, an endocrinologist at Harvard Medical School and the lead author of a new study, talks about the effects of declining...
Metabolic benefits afforded by estradiol and testosterone in both sexes
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As we very well know T s metabolites estradiol and DHT are needed in order to reap full beneficial effects of testosterone. Ts metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones...

Anastrozole - Enduring Side Effects 5 Years Later

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Hello all, I’m 28yo male in the US. When I was in my early 20s, I had a residual puffy nipple from puberty. I was very self conscious about this, being pretty deep in weight lifting, and my primary care physician prescribed an anti-estrogen...
High Estradiol in Men on TRT: What to Do
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Briefing Document: Estradiol in Men on TRT Source: Excerpts from "High Estradiol in Men on TRT: What to Do" by Nelson Viegel (excelmale.com) 1. The Role and Importance of Estradiol in Men Core Idea: Estradiol, often misconstrued as a solely...
Managing the Testosterone-to-Estradiol Ratio in Men on TRT
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Managing the Testosterone-to-Estradiol Ratio in Men on TRT Introduction Testosterone replacement therapy (TRT) in hypogonadal men often leads to an increase in estradiol (E2) levels due to the aromatization of testosterone. This alters the...
The TRT Guide from ExcelMale.com
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Understanding the Symptoms, Diagnosis, and Treatment of Hypogonadism in Men Hypogonadism, a condition characterized by low testosterone levels, can significantly impact a man's quality of life. ExcelMale.com offers a comprehensive guide to help...
What Every Man Needs to Know | Testosterone 101
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Testosterone is a key hormone for men's health, but what happens when levels drop? In this episode, Dr. Alex Tatem and KG break down everything you need to know about testosterone—what it is, signs of deficiency, when to get tested, and the best...
DHT and estradiol regulate fat in different areas of the body
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Testosterone metabolites differentially regulate obesogenesis and fat distribution Zachary L. Sebo, Matthew S. Rodeheffer Abstract Objective: Low testosterone in men (hypogonadism) is associated with obesity and type II diabetes...
Blocking Estrogen May Increase Fat in Men
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Recently published. "Only over the past few years have clinical intervention studies begun to confirm preclinical evidence that estradiol contributes to body weight regulation and metabolic health in men. One small study examined the effects of...
Controversies with Testosterone Replacement Therapy: Lecture by Dr Khera
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As usual Nelson's Excel is where it's at! Mohit Khera, MD, MBA, MPH, Professor of Urology, F Brantley Scott Chair in Urology, Medical Director of the Laboratory for Andrology Research, Medical Director for the Scott Department of Urology...
Estrogen is Essential for Muscle Growth in Bodybuilders
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William Llewellyn’s, ANABOLICS Estrogen Aromatization Testosterone is the primary substrate used in the male body for the synthesis of estrogen (estradiol), the principal female sex hormone. Although the presence of estrogen may seem quite...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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