Hot flashes and night sweats—collectively known as vasomotor symptoms (VMS)—are among the most disruptive yet frequently overlooked side effects experienced by men with low testosterone or those on testosterone replacement therapy (TRT). While...
By Nelson Vergel | ExcelMale.com | Updated December 2025 Introduction Should you take an aromatase inhibitor with testosterone replacement therapy? This question has sparked considerable debate in men's health circles, with some clinics routinely...
Side Effect Resource Directory Your Complete Guide to Managing TRT Side Effects Welcome to the Side Effect Management Resource Hub! This thread consolidates our best educational content on managing TRT side effects into one easy-to-navigate...
All the TRT tools you need — in one place, completely free. We're excited to announce the launch of our new Hormone Calculator Suite, designed specifically for the ExcelMale community to help you better understand and manage your hormone...
Dr. Rachel Rubin and Dr. Kelly Caspersen discuss with FDA Commissioner Dr. Marty Makary the significant impact of hormone replacement therapy (HRT) on women's health, particularly in the context of recent FDA changes to black box warnings. They...
Experiencing delayed orgasm or anorgasmia on TRT? Many men on testosterone therapy report difficulty reaching climax despite normal erections and libido. This frustrating issue is more common than most realize—and it's often treatable once you...
I hope you enjoy this part 1. Yes, it is almost 2 hours long but I concentrated everything I know so that you do not have to read for hours. What is low testosterone (hypogonadism) and how is it diagnosed? Low testosterone, or hypogonadism...
The FDA finally held a hearing on menopause—and it was long overdue. Georgie Kovacs breaks down the powerful expert testimony, the systemic failures, and why this matters for every woman navigating midlife care. In this grounded recap, you’ll...
Worried about testosterone replacement therapy side effects? You're not alone — but you may be surprised by what the science actually says. From high hematocrit to testicular shrinkage to fertility concerns, this guide walks you through every...
As we very well know T s metabolites estradiol and DHT are needed in order to reap full beneficial effects of testosterone. Ts metabolites estradiol and DHT are needed in healthy amounts to experience the full spectrum of testosterones...
Briefing Document: Hormonal Regulation of Male Sexual Desire, Arousal, and Penile Erection Source Rastrelli, G., Antonio, L., Carrier, S., Isidori, A., & Maggi, M. (2025). The hormonal regulation of men’s sexual desire, arousal, and penile...
Hello all, I’m 28yo male in the US. When I was in my early 20s, I had a residual puffy nipple from puberty. I was very self conscious about this, being pretty deep in weight lifting, and my primary care physician prescribed an anti-estrogen...
