It seems marijuana/THC can be an suppressor in men if used frequently enough, but I have yet to read/hear of any evidence that XXX oil reduces or negatively affects androgens.
I wasn't on it long enough to see how it affected my testosterone levels. Caused anxiety in me, the opposite of what most report. I took it nightly for about 2 weeks.
XXX in marijuana may worsen glaucoma, raise eye pressure
Research in mice suggests over-the-counter substance could possess unknown side effects
A study has found that XXX -- a major chemical component in marijuana -- appears to increase pressure inside the eye of mice, suggesting the use of the substance in the treatment of glaucoma may actually worsen the condition.
The study was done in mice, and I noted that the effect of raising IOP lasted about 4 hours, so if you use XXX at night, you may never notice the effect when you measure IOP in the daytime.
For some reason it seems to interfere with HCG rather drastically in my case. I couldn't figure out why all of the sudden I felt like I was crashing my levels after having just started XXX oil for sleep and pain. Apparently there are studies that show that leydig cells have receptors for cannabinoids and they can suppress testosterone production. So for someone on TRT, probably not an issue, but for someone on HCG monotherapy, potentially a big issue.
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