Why do I feel better when my hormones are in flux?

xibxang

Member
Hi everyone. Hope you're all well.

In late March my doctor changed my protocol and for about a month afterwards I felt great with a really decent libido. Then everything went flat. This isn't a new occurrence to me; it seems that I feel better whenever my hormones are in a state of flux. I've experienced it about a half a dozen times; it doesn't matter if my total weekly dosage is going up or down, or if I've merely changed the frequency at which I inject. Nothing really seems to give me the "feelgoods" unless my hormone levels are see-sawing. I've experienced the same thing with enanthate and cypionate.

Is this a common thing? Do any of you guys keep yourselves in a continual state of change to stay feeling good? Is there a protocol that would accommodate this?

I've contacted my doctor for advice but I thought I'd ask you guys too.
 
So with what kind of injection frequency do you feel good with en or cyp?
I like the convenience of every four days or even once per week. However, regardless of any frequency, I only ever seem to feel good in the four to six weeks directly after changing frequency and/or dosage. In that time I feel happy with good libido. Then after that initial period, everything falls flat again.
 
I often felt best when stopping testosterone on the tapering off period, high frequency always seems to mess me up eventually. Maybe you should try a very long injection interval with a slow ester, that way you would be in flux continuously.
 
In late March my doctor changed my protocol and for about a month afterwards I felt great with a really decent libido. Then everything went flat. This isn't a new occurrence to me; it seems that I feel better whenever my hormones are in a state of flux.
I experienced the same thing on injections, changing the dosage brought about a weeks worth of libido and erectile improvements, then it all disappeared.

This also happens in men who have abused steroids, and if still having these issues, there doesn’t seem to be a fix, at least in the near future.

Also remember, some EDC’s do block hormones at the receptors.

I theorize this positive response to changing hormones and improvements in libido and erectile function has to do with over-stimulation. These relatively short acting esters elevate hormones longer and more consistently, unlike natty men.

For years I had treatment failure on injections (cypionate/enanthate), and didn’t absorb T gel and T cream. I finally found something that allows me to have my cake and eat it too!

Jatenzo is very different from cypionate, with a half-life of 6 hours instead of 5-7 days. On Jatenzo, hormones peak in 2 hours, reaching midpoint at 6 hours and trough at 12 hours. This hormonal rise and rapid decline is why I believe it works so well for me.

No more feeling of over-stimulated, like on injections.
 
Last edited:

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
7
Guests online
396
Total visitors
403

Latest posts

Back
Top