Water Retention from HCG

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No, I got a regular e2 test from my doctor.

I feel great when my number is lower, like 5-10. It's tough trying to figure out how to manage AI to keep it consistently low without going too low. I get a lot of brain fog when I take too much arimidex.
 
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Gene Devine

Super Moderator
No, I got a regular e2 test from my doctor.

I feel great when my number is lower, like 5-10. It's tough trying to figure out how to manage AI to keep it consistently low without going too low. I get a lot of brain fog when I take too much arimidex.

The E2 lab you got is useless. The value you got is most likely well overstated.

You need the "Sensitive" assay to make an assessment on the use of an AI or else you stand to lower your E2 far lower then you expect and that's not a good place to be...trust me.
 

meelord

Member
So let me get this straight...If E2 is being driven more by the HCG than the test Cyp, the AI is useless? What do people on HCG monotherapy do to deal with elevated E2?
 

Nelson Vergel

Founder, ExcelMale.com
HCG and testosterone affect an enzyme that clears cortisol from the body. This can cause water retention. Some men seem to be more susceptible to this enzyme inhibition than others. It has absolutely nothing to do with estradiol.

Lowering the dose of HCG may help but may not be enough to maintain fertility or testicular size. I am exploring the use of a drug mentioned in this link.

Water Retention Caused by Testosterone May Have Nothing to Do with Estradiol
 

meelord

Member
Fair enough Nelson. I am reluctant to introduce something more that impacts blood pressure since I am already using Cialis. I am also in agreement that Arimidex is a tricky drug. What I do notice is the HCG is what seems to kick of symptoms like nipple and check skin sensitivity. This is a bummer since I do think the HCG helps with libido and obviously testicular size. In any event, I am trying to avoid swinging between the extremes of adding more meds versus simplifying my protocol.

Is it really true that an E2 spike generated by HCG can't be mitigated by taking Arimidex?
 

meelord

Member
I don't have any plan to go back on hCG mono. Being as I will have to be on TRT for life, I will be sticking with test cyp and any additions to maximize how I feel.


I don't know how to eliminate this issue of water retention with hCG. Maybe taking arimidex the same day as hCG?

So who is right? Does an AI work with elevated E2 via HCG or not? If so, no wonder it is so difficult to get E2 dialed in.
 

Vince

Super Moderator
So who is right? Does an AI work with elevated E2 via HCG or not? If so, no wonder it is so difficult to get E2 dialed in.

AI will lower your E2, no matter what reason it's high. Even if your not on TRT or just using HCG, AI will lower your estrogen.
 

bruin

Active Member
on 2 occasions I experienced water retention in my face and extremities, it was really only noticeable to me, but is was there.

I partially attribute it to my HCG, as I did not have this experience when solely on T. However, the condition slowly subsided, and I returned to " normal" status, and felt no real need to pursue an issue that has corrected itself.

I kinda stand by the mantra the body will correct itself and self adjust...........if all else is going well.
 

meelord

Member
AI will lower your E2, no matter what reason it's high. Even if your not on TRT or just using HCG, AI will lower your estrogen.

In the past two weeks I probably added 10 pounds of water weight. I am working on how to sequence HCG shots with my 100mg of Test C per week. I think HCG spikes my E2 given the amount of water weight I put on. I took .5 mg of Arimidex and I think I dropped 7 pounds of water weight in 36 hours. In addition, my blood pressure also dropped. I am getting ready to go out of town, but upon my return I am going to transition to daily injections and see if I can keep E2 under control without an AI. The HCG is emerging as a complicating factor.
 

Charlielegs

New Member
For many guys HCG complicates Estrogen management and that's what you're experiencing. Little known fact, the T to E conversion that happens in the testes, the organ youre stimulating with HCG, is not via the aromatase enzyme and is not affected by Anastrozole. Some men, like me, just don't like HCG or never find a dose or frequency that they can live with. At one-time I was using 100iu 2x a week just to keep my nuts alive as that is important for a host of reasons. But when it comes to sex drive, erections, a feeling of well being, HCG has never done that for me in any dose or combination.
So what did you end up doing? Curious because you sound exactly like me right now. Three years off and on hcg, can’t find correct dose. On clomiphene now but sex drive not great.
 
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