TRT Sub Q injections, now no more Anastrozole!

[chrismez]

Just a little background on me. 44 yrs old been on TRT for for over a year and half. When starting, total T at 152. Doc put me on 200mg per week on Test C and 2 Mg per week of Anastrozole. Was doing IM injections once per week, then stumbled on Dr Crisslers subq video and decided to give it a try. 200mg per week put me from 820-934 TT average based on several blood tests. Estradiol from 15-27 average from IM injections.

Fast forward to the last 6 months. Subq injectiosn of 80mg Test C E3D and .25 mg of Anastrozole. Did a bunch of research on more frequent, smaller dose injections. Also read that smaller more frequent subq doses would cause less conversion the T to E. Felt really good for awhile then did blood work 2 months ago and my TT was 880 but Estadiol showed <6. Sex drive dropped off severely and was tired. Decided to lower my Anastrozole to .25mg per week and just received my blood work results last week. TT at 820 and E still <6. I'm going to stop taking the Anastrozole and do blood work again in 6 weeks and see the results. The longer I have done the subq injections it seems my requirement for Anastozole has gone down. Starting to believe that sub q injections are the way to go....been week and a half of no AI and I feel better all ready, sex drive improving and not really tired. Curious if anyone else has had the same experiences???

 

[Nelson Vergel]

When I did not know what I was doing years ago, I also tanked my estradiol. I took weeks to get it back up to the 20-40 pg/mL (sensitive test) range. I am glad you stopped anastrozole.

Most guys using lower dose and more frequent injections do not need anastrozole since their estradiol never peaks that high.

 

[chrismez]

Thanks Nelson, I appreciate the response. The labcorp ratio is 347-1197. I plan on doing trt for life unless something in my BW tells me I have to stop. In your opinion, what's a good level to be at? My doc wants me to be at the higher end of the normal range but never really gave me specific number. Most of the time 80mg E3D which averages out to 200Mg per week puts me anywhere from 820-934 TT based on numerous blood tests, but most of the time they are in the 800's. Blood tests are done just before my next injection. I know so my people get hung up on dosage amounts and not Test levels...

 

[Nelson Vergel]

Having TT levels above 700 ng/dL usually makes guys feel better. However, keep in mind the need to monitor for the following ranges:

Blood Tests Needed Before and During Testosterone Replacement Therapy

 

[CoastWatcher]

Thanks Nelson, I appreciate the response. The labcorp ratio is 347-1197. I plan on doing trt for life unless something in my BW tells me I have to stop. In your opinion, what's a good level to be at? My doc wants me to be at the higher end of the normal range but never really gave me specific number. Most of the time 80mg E3D which averages out to 200Mg per week puts me anywhere from 820-934 TT based on numerous blood tests, but most of the time they are in the 800's. Blood tests are done just before my next injection. I know so my people get hung up on dosage amounts and not Test levels...

Too many get hung up on dosage amounts, and test levels...and not how they feel. Give it some time and balance how you feel with what your labs tell you. I had a steady total testosterone value of 1035 - and felt much better when I modified my protocol and maintained it in the mid-800s. Each of us is different. Good luck!

 

[Vince]

Too many get hung up on dosage amounts, and test levels...and not how they feel. Give it some time and balance how you feel with what your labs tell you. I had a steady total testosterone value of 1035 - and felt much better when I modified my protocol and maintained it in the mid-800s. Each of us is different. Good luck!

We all are very different, I feel better when my total testosterone levels are over 1000.

 

[chrismez]

I'm gonna bump it up to 90mg E3d and see how that works out... Will update after next blood work is completed..

Chris

 

[CoastWatcher]

You mentioned you were following the technique Dr. Jon demonstrated in his video. Did you modify it all? Congratulations on your success.

 

[jfullam]

I just started with Defy with the following protocol (under Dr. John Crisler):
Test Cyp 60 mg 2x per week subq
HCG 100iu Daily subq
Estradiol was at 16.9 with my last BW
I plan to monitor my Estradiol levels closely and also hope to avoid taking any Anastrazole.

 

[chrismez]

You mentioned you were following the technique Dr. Jon demonstrated in his video. Did you modify it all? Congratulations on your success.

I started out at 200mg IM injection once a week. I found Dr Jon's video on youtube then started doing E3D Injections with a 27G 1/2 cc syringe. Kept reading on the more frequent injections cause less spikes. I inject in the belly and it's quite painless. I told my Doc what I was doing and he was cool with it even though he has all patients doing IM. I use privatemdlabs to check my blood work every couple months and started adjusting the Anastrozole based on my lab results to get to my E to around 22 which my Doc said is optimal.

 

[Vince Carter]

I'm gonna bump it up to 90mg E3d and see how that works out... Will update after next blood work is completed..

Chris

Thing I will suggest for you is how I got off Anastrozole and that was driven by my SHBG but I shoot TCyp EOD. What I want you to consider is getting your shots closer together and smaller doses. I do not think you'll find what you're looking for by upping it to 90 at one-time. Key to know with the Estrogen conversion is the more shoot at one-time, the more will aromatize as it is excess to what you need.
I've been off Anastrozole for a about a month now and I've been tanked on E2 and overmedicated with Anastrozole, it's not a pleasant place to be. It's my belief that some men that complain about the benefits of HRT not working for them, that they're being mismanaged on Estrogen levels.

 

[CoastWatcher]

It's my belief that some men that complain about the benefits of HRT not working for them, that they're being mismanaged on Estrogen levels.

Absolute truth.

Please consider pulling your levels via Discountedlabs.com (or another service). Pay attention to your body and test regularly.

 

[Vince Carter]

That's how I did it, I was keeping notes, and getting labs

 

[chrismez]

I do my labs every 2 months. Doc gives me full tests every year. I do the female hormone panel test on privatemdlabs. Cost $56 and gives you total T, E, metabolic panel, CBC and few others. It's cheap and I guess I obsess a tad on where I'm at level wise...Get results in about 1 day. I've been doing the 80mg E3d for the past 6 months and I've noticed my need for Anastrozole has continued to decrease to the point where .25mg a week I still show at <6. It's been 10 days since I've taken the AI and I feel better. @Vince. So you think doing 50-55mg EOD would be better than 90 E3d?

 

[Jay]

chrismez,

You never stated what your Total T was on one shot per week of 200 mg...Do you remember what it was?

Sometimes going out of town I do one shot...just wondering how that stacks up to EOD shots.

 

[chrismez]

chrismez,

You never stated what your Total T was on one shot per week of 200 mg...Do you remember what it was?

Sometimes going out of town I do one shot...just wondering how that stacks up to EOD shots.[/QUOTE

Took my blood test just before my next injection and I believe it was 848.. But that was 6 days after so im guessing I was really high a couple days after and it slowly came down. I noticed no difference in T numbers between Im and Sub q injections. But I personally feel better on Sub Q.. Might be a combo of the subq and more freq injections.

 

[chrismez]

Just a update. Will be doing my blood work this Friday and will post results asap, most likely Saturday. Currently doing 60mg EOD Subq and no Anastrazole. Its been 5 weeks on this protocol. Feel pretty good, sex drive decent.

 

[Vince Carter]

That's great, I've been pushing the EOD and no Anastrozole angle, it's worked for me. I'm at 50mg EOD and (standard test) E2 is @ 42. This is the best I've felt since I started. TT @ 1031.

 

[chrismez]

Ok, just got my results and here they are. Total t 934 and E at 7.0. This had been for 5 weeks at 60mg EOD sub q injections for a total 210mg per week and no anastrozole. I would of thought my E would of been higher. Any suggestions on why its still really low? Does it take a long time for E to rise??? RBC was fine but ALT was 61 and AST was 50. A tad high but I did just get back from a cruise and was boozing it pretty good. Was doing hard cardio workouts just prior to my blood test which I read can affect those liver markers as well...

 

[Vince Carter]

I'd retest the E2, that has to be a fluke, or rule out lab error. I'd think on 210/week you'd be over 1000 TT, too.