TRT almost a year now...suddenly lost all motivation to work out

Do you have LH and FSH labs? supposedly these have effect of hormone processes and functions elsewhere (ie... adrenals, thyroid, liver, etc)..... I have low SHBG, LH and FSH was completely shut off and I was having no motivation (mental) to want to work out either although sex drive was still OK.... Anyway, I just started HCG (pregnyl) 250iu x 3/wk..... Im hoping to restart LH/FSH production and see if it has any effect on the other hormones....
hCG acts as an LH replacement; it does not restart production of LH or FSH. For restarting you would need to try a SERM. Conventional wisdom has said these are useless on TRT, but there's starting to be some evidence that they can work, perhaps if the TRT dose is on the lower side. Defy Medical is said to have some patients doing this.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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