madman
Super Moderator
41:48-52:44 (DHT and estradiol)
The medical landscape of testosterone replacement therapy is shrouded in mixed opinions and, much more seriously, in misconceptions…
That’s why I sought out the man who is widely known and internationally respected as the “Father of Testosterone Therapy,” Dr. Abraham Morgentaler.
Dr. Abraham Morgentaler is a board-certified urologist, renowned medical researcher, and entrepreneur most recognized for his role in elevating men’s health to an emerging clinical specialty of crucial importance.
Dr. Morgentaler’s clinical and research findings boldly inverted the traditional urological medical community’s previous assumptions about testosterone levels. We cover it all in today’s episode - from the truth about whether TRT really causes prostate cancer, to the pros and cons of aromatase inhibitors, to the significant differences between free T and total T.
If you’re a man who prioritizes your family, fitness, and business, this is one episode you will NOT want to miss.
You'll learn:
- The Pros and Cons of Aromatase Inhibitors
- Differences Between Free T and Total T Levels
- Debunking the Myths of Testosterone Replacement Therapy
- How to Properly use hCG and Clomid Treatment
- The FIRST Intervention for Weight Loss and Hypogonadism
Timestamps:
0:00 Intro to Dr. Morgentaler
5:45 Debunking myths around testosterone use.
11:00 What we learned about men from lizards.
17:15 Generational decline in male testosterone levels.
22:30 The discrepancies of lab reference ranges.
28:00 The problem with "normal" versus "low" testosterone.
31:00 Total testosterone versus free testosterone.
38:30 The defining secret about low testosterone.
45:00 The scoop on estradiol and anastrazole.
50:00 TRT and weight gain; why men need estradiol.
56:00 Weight loss, TRT, drive, and motivation.
1:02:00 What about obesity and TRT?
1:06:00 Where to learn more from Dr. Morgentaler.
The medical landscape of testosterone replacement therapy is shrouded in mixed opinions and, much more seriously, in misconceptions…
That’s why I sought out the man who is widely known and internationally respected as the “Father of Testosterone Therapy,” Dr. Abraham Morgentaler.
Dr. Abraham Morgentaler is a board-certified urologist, renowned medical researcher, and entrepreneur most recognized for his role in elevating men’s health to an emerging clinical specialty of crucial importance.
Dr. Morgentaler’s clinical and research findings boldly inverted the traditional urological medical community’s previous assumptions about testosterone levels. We cover it all in today’s episode - from the truth about whether TRT really causes prostate cancer, to the pros and cons of aromatase inhibitors, to the significant differences between free T and total T.
If you’re a man who prioritizes your family, fitness, and business, this is one episode you will NOT want to miss.
You'll learn:
- The Pros and Cons of Aromatase Inhibitors
- Differences Between Free T and Total T Levels
- Debunking the Myths of Testosterone Replacement Therapy
- How to Properly use hCG and Clomid Treatment
- The FIRST Intervention for Weight Loss and Hypogonadism
Timestamps:
0:00 Intro to Dr. Morgentaler
5:45 Debunking myths around testosterone use.
11:00 What we learned about men from lizards.
17:15 Generational decline in male testosterone levels.
22:30 The discrepancies of lab reference ranges.
28:00 The problem with "normal" versus "low" testosterone.
31:00 Total testosterone versus free testosterone.
38:30 The defining secret about low testosterone.
45:00 The scoop on estradiol and anastrazole.
50:00 TRT and weight gain; why men need estradiol.
56:00 Weight loss, TRT, drive, and motivation.
1:02:00 What about obesity and TRT?
1:06:00 Where to learn more from Dr. Morgentaler.
- 00:00 ️ Introduction to the Podcast and Guest Speaker
- Introduction to the podcast focusing on male sexual function, hormone optimization, and dispelling myths.
- Dr. Abraham Morgentaler's expertise and credentials introduced.
- Sponsorship mention for Water and Wellness products.
- 04:09 Water and Wellness Sponsorship Plug
- Promotion of water filtration products from Water and Wellness.
- Recommendation for aqua true countertop water filter and ketone supplements.
- Emphasis on the importance of clean water for health and vitality.
- 05:03 Testosterone Replacement Therapy (TRT) Myths and Realities
- Discussion on the historical misconceptions and fears surrounding testosterone replacement therapy (TRT).
- Dr. Morgentaler's journey of challenging beliefs about TRT and its effects on prostate health.
- Evidence supporting the safety and benefits of TRT in improving men's health and quality of life.
- 10:17 Declining Testosterone Levels and Possible Causes
- Exploration of the proposed decline in testosterone levels across generations.
- Factors contributing to declining testosterone levels, including obesity and environmental pollutants.
- Speculation on the long-term implications of declining testosterone levels for human health and fertility.
- 22:33 Understanding Testosterone Reference Ranges
- Testosterone reference ranges vary over time and can differ between labs.
- Reference ranges are based on a supposedly healthy population, but what defines "healthy" can vary.
- There's significant variability among labs in establishing reference ranges, leading to confusion for patients and physicians alike.
- 30:31 Importance of Free Testosterone Levels
- Free testosterone levels are a better indicator of a man's testosterone status than total testosterone.
- Symptoms of testosterone deficiency correlate more closely with free testosterone levels.
- Despite the importance of free testosterone, many physicians focus on total testosterone due to uncertainty and lack of reliable testing methods for free testosterone.
- 36:35 Strategies to Increase Free Testosterone
- Increasing free testosterone is a goal for some, as it is the biologically active form of testosterone.
- Free testosterone can be increased by reducing sex hormone-binding globulin (SHBG) levels.
- Alternative medicine approaches may suggest using supplements like nettles or DIM, but their efficacy and reliability are uncertain and lack scientific evidence
- 45:37 High Estradiol Concerns and Arimidex Use
- High estradiol levels have been associated with increased risks of certain health issues, including cardiac deaths and heart disease.
- Some physicians prescribe Arimidex, anastrozole, to block the conversion of testosterone to estradiol, but it's not universally recommended.
- There's debate about the necessity of Arimidex since high estradiol levels in men on testosterone therapy may not directly cause negative outcomes.
- 48:14 Arimidex Usage and Alternatives
- Arimidex is commonly prescribed alongside testosterone therapy to prevent estrogen elevation.
- Dr. Morgentaler shares his reservations about routine Arimidex use, citing his extensive experience with testosterone therapy.
- Gynecomastia (breast tissue swelling) is a rare side effect of high estradiol levels, but it can be managed with Arimidex.
- 52:48 HCG and Clomiphene for Testosterone Therapy
- Human chorionic gonadotropin (HCG) and clomiphene are alternative treatments for men with low testosterone levels, particularly those concerned about fertility.
- HCG mimics luteinizing hormone (LH) and stimulates testosterone production in the testicles, preserving testicular size and fertility.
- Clomiphene, although not FDA-approved for men, can improve sperm counts and raise testosterone levels, but it may not be as effective as HCG or testosterone replacement.
