The Long Haul: Treating Men with Obesity with Testosterone

DragonBits

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The Long Haul: Treating Men with Obesity with Testosterone

  • BY DEREK BAGLEY
  • JUN 2019
A study presented at ENDO 2019 shows that long-term testosterone therapy in men with obesity and hypogonadism can actually contribute to prolonged weight loss without an added risk for mortality or major cardiovascular incidents.
  • At a Glance

Obesity – a complex physiological disorder – is more common in men with hypogonadism.
A study presented at ENDO 2019 showed that men with hypogonadism and obesity lost weight and were able to keep the weight off long-term.

Testosterone treatment not only reduced weight, but also the risk for mortality and major adverse cardiovascular events.

The Long Haul: Treating Men with Obesity with Testosterone - Endocrine News
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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