The Death of the ‘Testosterone Causes Prostate Cancer’ Myth: What Every Man on HRT Needs to Know

madman · Jun 30, 2026

Thread 'Helen L. Bernie, DO, MPH, on counseling patients through TRT and prostate cancer uncertainty'

Jun 30, 2026

The FDA's proposed narrowing of the testosterone therapy prostate cancer contraindication to metastatic disease only reflects current clinical evidence, opening the door to testosterone therapy in appropriately selected men with treated localized prostate cancer or on active surveillance, with shared decision-making and PSA-testosterone co-monitoring as the foundation of responsible care, as Helen L. Bernie, DO, MPH, outlines in this interview.

madman · Jul 6, 2026

Thread 'FDA's Newest Testosterone Update | What Men Need to Know'

Jul 6, 2026

In this episode, Dr. Brandon and Dr. Morgentaler talk about the FDA's groundbreaking testosterone label changes, the evolving evidence on testosterone therapy and prostate cancer, and how quality of life should factor into treatment decisions for men with advanced disease.

Time stamps:

00:00 Listener Question Metastatic Prostate Cancer – Dr. Morgentaler explains whether testosterone or anabolic steroids may have a place in treating men with metastatic prostate cancer while preserving quality of life.

04:09 Testosterone Quality of Life...

madman · Jul 11, 2026

Thread 'Treatment of Prostate Cancer: Testosterone and PCa - From Dogma to Data'

Jul 11, 2026

Helen L. Bernie, DO, MPH, Director, Sexual and Reproductive Medicine and Assistant Professor of Urology, Indiana University, Carmel, Indiana, presents a review of testosterone therapy in men with prostate cancer, focusing on current evidence and clinical management.

She examines the historical belief that testosterone promotes prostate cancer progression and traces this concept to early studies with limited data. Contemporary evidence is reviewed, including observational studies, retrospective analyses, and randomized trial data evaluating the safety of...

madman · Aug 6, 2026

Thread 'Neil Baum, MD, and Abraham Morgentaler, MD, discuss the history of testosterone and prostate cancer'

Aug 6, 2026

Abraham Morgentaler, MD, joins Neil Baum, MD, to discuss the historical origins of the belief that testosterone drives prostate cancer and the new framework presented in his recent Journal of Urology publication.

madman · Friday at 10:21 PM

Thread 'Miller School Trial Tests Testosterone Therapy in Men With Low-Risk Prostate Cancer'

Friday at 10:00 PM

* “Active surveillance is about safely managing low-risk prostate cancer while preserving quality of life,” said Sanoj Punnen, M.D., professor of urologic oncology at the Miller School and DSUI vice chair of research. “For some men, maintaining quality of life may include testosterone supplementation. While historical dogma raised concerns about testosterone use in men with prostate cancer, many urologists now believe it can be used safely in carefully selected men on active surveillance with appropriate monitoring. The challenge is that we still lack...