Testosterone Use During Illness

DorianGray

Active Member
Recently, hit with bad virus, severe sore throat, no fever. Reading that T has something of immunosuppressive effects, so what is the consensus, continue regimen or stop until symptoms subside?
 
 
Recently, hit with bad virus, severe sore throat, no fever. Reading that T has something of immunosuppressive effects, so what is the consensus, continue regimen or stop until symptoms subside?
I would think just the opposite. For example, estrogen has (innate) immune system benefits so doing something that might lower it (via removing a precursor) would not be desirable, and neither would reducing your overall vitality. What are you basing the idea on? The only thing I saw after a quick search was related to vaccine response which is not the part of the immune system you should be focusing on. What you want is strong innate immune function as well as all the usual anti-viral protocols that were well-described during covid.

I hope you get better soon.
 
People admitted to hospitals are more likely to recover more quickly, and even have a decreased risk of dying in the ER with higher testosterone. Also, men with lower testosterone are more likely to die from covid.

When I had sciatica pain that required a needle in my spine, physical therapy was a challenge trying to build up muscle with low-T, getting nowhere fast!
 
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I would think just the opposite. For example, estrogen has (innate) immune system benefits so doing something that might lower it (via removing a precursor) would not be desirable, and neither would reducing your overall vitality. What are you basing the idea on? The only thing I saw after a quick search was related to vaccine response which is not the part of the immune system you should be focusing on. What you want is strong innate immune function as well as all the usual anti-viral protocols that were well-described during covid.

I hope you get better soon.
Thanks. Yes, going back, I see some literature referenced influenza vaccine immune response. Another paper, looking to extrapolate T effects (or inhibition of) related to covid, generally concluded: "...These observations confirm that androgens have an immunosuppressive effect..." Others, counter that conclusion to the extent of no effect. On the other side of the coin, random literature search on immune effects of HCG pointed to more positive effects. I hadn't been sick in so long, this was really a pain, especially since I left on vacation the day it was coming on. Main symptom was it felt like someone blow torched my throat. Hardly any other symptoms. 90% ok now.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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