Testosterone levels keep dropping

SHBG decreased. That's pretty much the answer here.

Thank John. The problem is when i dropped testosterone dosage from 70mg to 60mg twice a week i also added tamoxifen that increased my SHBG.
But look at my labs when SHBG was 21.7 my testosterone dosage was 50mg twice a week (no tamoxifen here)
Then i increase dosage to 56mg twice a week and with a SHBG of 26.2 my total T dropped from 890 to 770. So this is why i think SHBG doesn't explain these results.
What do you think?
 
Thank John. The problem is when i dropped testosterone dosage from 70mg to 60mg twice a week i also added tamoxifen that increased my SHBG.
But look at my labs when SHBG was 21.7 my testosterone dosage was 50mg twice a week (no tamoxifen here)
Then i increase dosage to 56mg twice a week and with a SHBG of 26.2 my total T dropped from 890 to 770. So this is why i think SHBG doesn't explain these results.
What do you think?

That isn't a huge decrease.
 
I increase my dosage to 140mg (70mg E3.5D) from 120mg. My Total T came back at 798 (250-1100). Previous blood work Total T came at 770 (using 120mg week). There was a difference in the time I drew blood. This time I drew blood just before injecting saturday morning. Previous time I drew blood tuesday morning (12 hour before injecting). So that will have a impact.
I have been on TRT for 2 years and i feel my best when my total T is around 1200.
For the guys that switched to daily injections. How much do you think my total T will increase if i switch to 20mg daily injections? I currently take 0.25mg anastrozole E3D and my sensitive estradiol is 21 (range <29). Wondering if i switch to daily injections i can both increase my total T levels back to 1200 and maybe get rid of anastrozole.
I would love to try subq. Last time i did injecting 0.35ml i got bad lumps. Maybe 0.1ml daily injections i might not have lumps given the lower volume
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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