yes it is crazy how T3 raises SHBG! mine went from 35 to 60 when i raised my FT3 to 5.5 now trying to get back down to a spot that works and bring my SHBG down with it. I am now back down to 2 grains of desiccated thyroid.mine stayed the same. surprising to me cytomel really jacked up my SHBG. to the tune of about 3X
Sorry last sentence meant to say: maybe this happens to men whow have low SHBG to start with.Actually the complete opposite happened to me. My baseline T was 400 and my SHBG was 82. 8 months later my T is 1230 and my SHBG is 53. I never saw an increase of SHBG with higher testosterone. Maybe this happens to me who have low SHBG to start with?