Systematic use of HCG can burn the testicles?

clonda

New Member
Hi guys! I read in one article that the use of hCG in the long term can "burn" the testicles and in the future they will lose sensitivity to gonadotropins. This question is very relevant in hormone replacement therapy, when it is necessary to systematically inject hCG to maintain the testicles. Is there any information about this?
 
Hi guys! I read in one article that the use of hCG in the long term can "burn" the testicles and in the future they will lose sensitivity to gonadotropins. This question is very relevant in hormone replacement therapy, when it is necessary to systematically inject hCG to maintain the testicles. Is there any information about this?
This is why I am taking a year break from HCG then back on for couple months then back off. Thanks for the info!
 
Hi guys! I read in one article that the use of hCG in the long term can "burn" the testicles and in the future they will lose sensitivity to gonadotropins. This question is very relevant in hormone replacement therapy, when it is necessary to systematically inject hCG to maintain the testicles. Is there any information about this?
Not the amount we use on TRT. 500 IU twice a week or even three times a week will not harm your testicles.
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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