It's just creating a lot more stability and consistency with your serum levels at 2x/wk ... Peak value is usually at the 2 to 3 day range, 1/2 life being 7 to 8 days. Reducing to 2x per week will reduce the peaks and troughs (as you know); with a continuous administration of smaller dosages during the "peak" window. Another key benefit is that lowering these spikes will also help with keeping estradiol managed, as downstream conversion will be also be noticeably more stable. No AI in three (3) years on this end ... It works!
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
Enter your total testosterone value to see predictions
Results will appear here after calculation
A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038