Sexual Dysfunction Lecture by Nelson Vergel- Video and Summary

[Nelson Vergel]

00:00 - 10:10​

• The speaker discusses sexual dysfunction in men and women, focusing on erectile dysfunction.
• The lecture covers various causes and risk factors for erectile dysfunction, including age, cardiovascular disease, diabetes, and psychological issues.
• The speaker also discusses the pharmaceutical industry's treatment for erectile dysfunction, including compounded products and oral medications.
• The prevalence of erectile dysfunction is discussed, with a focus on the impact on relationships and overall health.
• The lecture also addresses the relationship between sexual dysfunction and low sex drive, as well as the influence of factors such as stress, fatigue, and substance use.

09:53 - 20:00​

• Sexual dysfunction can be caused by various factors such as guilt, stress, relationship problems, excessive alcohol and drug use
• Differentiating between psychological and organic causes of erectile dysfunction (ED) can be determined by the presence of nighttime erections
• Medications, lifestyle factors, and physiological mechanisms can also contribute to sexual dysfunction
• Nitric oxide plays a key role in the physiological mechanisms of erections and is inhibited by PDE5 enzymes, leading to the development of drugs like Viagra
• Libido and erectile function can be affected by sleep, diabetes, and high blood pressure, and testosterone replacement may not always meet expectations
• Libido is cyclical and can be influenced by nature, and the acceptance of this natural cycle is important
• Erectile dysfunction treatment options have evolved over time, with limited options available in the past

19:51 - 29:51​

• The speaker discusses the history of treatments for erectile dysfunction
• They mention the use of goat testicles, penile vacuum pumps, and penile implants
• They talk about the development of Viagra and other drugs for erectile dysfunction
• The speaker also emphasizes the importance of intimacy and companionship in relationships, especially as people age
• They mention the availability of different treatments for erectile dysfunction, including PD5 inhibitors and penile injections
• The speaker also discusses the importance of sex therapy for addressing issues related to anxiety and performance anxiety

29:45 - 39:48​

• Empower Pharmacy only offers PD-5 inhibitors in the ODT dosage form at this time
• PD-5 inhibitors are commonly used to treat erectile dysfunction in men by increasing the amount of a compound called CGMP
• A comparison table of Viagra, Levitra, Cialis, and Stendra was discussed, highlighting their doses, peak time, and side effects
• Cialis is popular due to its long half-life and can also be used for enlarged prostates
• The cost of these medications is a driving force for seeking alternative options like compounding pharmacies
• ODT formulations are a new option that dissolve under the tongue and are cheaper than trochies
• The availability and cost of these medications are important factors for patients
• Contraindications for PD-5 inhibitors include low blood pressure and use of organic nitrates for cardiovascular disease

39:33 - 49:37​

The speaker discusses the use of organic nitrates for cardiovascular disease and their potential interactions with other medications. They also mention the use of Norveer as a booster for HIV medications and the potential side effects of prolonged erections from injections for erectile dysfunction. The speaker emphasizes the importance of patient education and proper administration techniques for these medications. They also mention different formulations of injections and the availability of an antidote for prolonged erections.

49:32 - 59:54​

• The speaker discusses the use of injectable treatments for erectile dysfunction, including Trimix and Carverjet
• He also talks about other options such as penile implants and vacuum constriction devices
• The speaker also addresses female sexual dysfunction and the challenges in defining and treating it
• He emphasizes the importance of clitoral stimulation for female orgasm and the need for better communication and understanding in sexual partnerships

59:32 - 01:09:35​

• The speaker discusses the complexities of sexual function, including the impact of mental, physical, and hormonal factors.
• They emphasize the importance of addressing sexual dysfunction in women, including issues related to menopause, hormonal fluctuations, and breast cancer survivors.
• The speaker also discusses the use of testosterone and Viagra for women, as well as other products to address vaginal atrophy and dryness.
• They highlight the need for more research and education in the field of female sexual health.

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01:09:23 - 01:19:43​

• Various medications can affect sexual desire and arousal, including antidepressants, hormonal contraceptives, statins, and blood pressure medications
• Treatments for female sexual dysfunction include antidepressants, Viagra, and PT-141
• Compounded products like "scream cream" are popular for enhancing female sexual function
• There is a growing market for medications and treatments targeting female sexual health, with potential for growth and opportunity for companies in this space.

01:19:21 - 01:29:24​

• The discussion is about the use of topical cream for absorption directly into the receptor sites
• Oral ingestion of certain ingredients requires higher doses for systemic effects
• The effectiveness of different formulations of the cream and the absence of testosterone in some formulations is discussed
• The use of L-arginine in the cream and its potential impact on patients with herpes simplex is also discussed
• The use of prostaglandin in BiMix and the refrigeration requirement for reconstituted products is also addressed

01:29:00 - 01:33:06​

• The discussion covers the importance of refrigeration for reconstituted products
• Concern is raised about the overuse of medications in younger generations, leading to sexual dysfunction and hormone imbalances
• Lifestyle factors such as electronics and obesity are also highlighted as contributing to sexual and hormonal issues
• The importance of sleep and the negative effects of electronics on sleep quality are emphasized
• The need for dialogue and sharing of information through email and videos is encouraged
• Plans to transcribe and create booklets from the videos for further education and training are mentioned
• The session is concluded with thanks and encouragement for practical application of the information in daily life,

​

TOPICS:
00:00 - 09:53​

sexual dysfunction
erectile dysfunction
age
women
men
products
compounding
penile injections
BD5 inhibitors
oral products
ocytocin
orally disintegrating tablets
testosterone
libido
cardiovascular disease
diabetes
high lipids
cholesterol
obesity
depressive symptoms
pharmaceutical industry
prevalence
causes
psychological aspects
hormonal factors
vascular issues
neurological causes
organic causes
risk factors
psychogenic issues
anxiety
depression
fatigue
sex drive

09:53 - 19:50​

sexual dysfunction
psychological factors
organic factors
erection
libido
testosterone replacement
nitric oxide
PDE5 inhibitors
Viagra
desire
sleep habits
hormones
antidepressants
relationship problems
obesity
stress
alcohol abuse
diabetes
heart disease
high blood pressure
neurological diseases
vascular disease
high cholesterol
medications
orgasmic dysfunction
physiological mechanisms of erections
libido cycles
erectile dysfunction treatments

19:51 - 29:44​

Erectile Dysfunction
Sexual Behavior
Penile Implants
Viagra
Testosterone
PD5 Inhibitors
Sex Therapy
Intimacy
Mues
Carverjet

29:45 - 39:32​

PD-5 inhibitors
erectile dysfunction
medication dosage forms
Viagra
Levitra
Cialis
Stendra
side effects
compounding medications
insurance coverage
cost of medications
patient education
OTD formulations
treatment options
drug contraindications
pharmacokinetic data
drug availability
patient-driven market
pharmacy formulations
dissolving tablets
drug contraindications
blood pressure management

39:33 - 49:32​

Organic nitrates
Cardiovascular disease
Blood pressure
HIV
Norveer
Boosters
Injection technique
Erectile dysfunction
PD5 inhibitors
Prior prism
Fibrosis
Trimix
Super trimix
Antidote
Empower
Sudafed
Prescription
Fibrosis treatment
Sudafed oral

49:32 - 59:32​

Sudafed
erection
injectables
testosterone
penile prosthesis
vacuum constriction device
Carverjet
female sexual dysfunction
orgasm
clitoral stimulation
male performance
libido
arousal disorder
orgasmic disorder
pain disorder
sexual intercourse

59:32 - 01:09:22​

Sexual Dysfunction
Testosterone for Women
Vaginal Atrophy
Female Sexual Health
Menopause
Viagra for Women
Estrogen Therapy
Female Dysfunction Medications

01:09:23 - 01:19:20​

Pharmaceuticals and their effects on sexual desire
Treatment for sexual disorders in women
Antidepressant treatments for sexual dysfunction
Psychological support for sexual pain disorders
Therapies for urinary syndrome and painful sex
Transdermal testosterone and estrogen therapy
PT-141 as a potential drug for sexual function
Scream cream for female sexual function
Compounded products for sexual enhancement
Market opportunities in female medicine

01:19:21 - 01:29:00​

Topical cream
Absorption
Oral medication
PD-5 inhibitors
L-arginine
Cream base
Vasodilator
Trimix
Erections
ScreamCream
Testosterone
Libido
Lubrication
Arginine
Herpes simplex
Prostaglandin
BiMix
Refrigeration
Stability

01:29:00 - 01:33:06​

traveling
refrigeration
reconstituted products
antihistamines
antibiotics
birth control
antidepressants
anti-anxiety medications
sleep medications
sexual dysfunction
hormone levels
prescription drugs
alcohol
electronics in bed
sleep deprivation
REM sleep
sexual health
lifestyle
obesity

 

[Nelson Vergel]

The video discusses various treatments for sexual dysfunction in men, including penile injections, which require education and can cause side effects such as fibrosis and priapism. The speaker recommends trying other options before resorting to injections and emphasizes the importance of patient education. The video also briefly mentions sexual dysfunction in women, noting that there is no one-size-fits-all definition and that the FDA has had difficulty approving effective treatments.Penile injection with trimix is a popular treatment option, but requires patient education and can lead to side effects such as fibrosis.✦Penile injections for long erections require patient education

.00:01✦Trimix injection is an effective treatment for erectile dysfunction.

07:30✦Female sexual functioning is complex and has many factors

13:33✦Low testosterone levels in women can lead to sexual dysfunction

00:22✦Estrogen therapy can restore vulva flow after menopause.

26:22✦PT-141 is a new drug in development that enhances sexual function and libido for both men and women

33:15✦Topical cream for women's health presents a new market opportunity

38:21✦Avoid active breakouts with oral arginine and lysine supplementation

01:18✦Populations are sleep-deprived and not reaching REM sleep