madman
Super Moderator
The Risk of Sexual Dysfunction and Effectiveness of Treatment of Benign Prostatic Hyperplasia With Severe Lower Urinary Tract Dysfunction With Combination of Dutasteride and Solifenacin
CONCLUSION
Overall sexual function in men with BPH and severe LUTS is not impaired by prolonged intake of double dosage of solifenacin combined with dutasteride. Sexual satisfaction of men at the end of the sixth month of combined therapy course becomes higher than the initial one. This combination does not impact on erectile function but fractionally decreases ejaculation function. However, the overall assessment of sexual function by patients is quite high. The combination of dutasteride and doubled dosage of solifenacin causes a rapid reversibility of obstruction and hyperactivity symptoms typical for BPH with severe LUTS and is not accompanied with the increase of side effects.
CONCLUSION
Overall sexual function in men with BPH and severe LUTS is not impaired by prolonged intake of double dosage of solifenacin combined with dutasteride. Sexual satisfaction of men at the end of the sixth month of combined therapy course becomes higher than the initial one. This combination does not impact on erectile function but fractionally decreases ejaculation function. However, the overall assessment of sexual function by patients is quite high. The combination of dutasteride and doubled dosage of solifenacin causes a rapid reversibility of obstruction and hyperactivity symptoms typical for BPH with severe LUTS and is not accompanied with the increase of side effects.
