I've only been on it 3 weeks now. I had a doctor appointment this morning and the scale reflected a 6 pound loss. My main goal is to help with my lipodystrophy. From what I've read, it's still too soon to see the other benefits such as increased muscle gain or better skin which would all be lagniappe for me. I'll be sure to keep you posted as I progress. I have noticed an improvement in my sleep but that could also be a result of my new CPAP machine, or a combination of both. I can confidently say I'm moving forward and feeling much better all the way around.