Second honeymoon. Will it also crash?

Does diurnal effect even apply to guys on TRT?
I mean your natural T production is shutdown. All T comes from a needle the only rhythm is how frequest you inject.

The closest one could get to mimicking the natural diurnal rhythm of testosterone of a healthy young male is using the testosterone patch or transdermal (when only applied once daily) and even than most would need double the dose when using patches or higher doses of transdermal to attain high/normal physiological testosterone levels. As far as injections they cause steady state and in no way mimic the natural diurnal rhythm albeit injecting daily would result in the most consistent levels although still steady state.
 
How did you find that out?

As many people, I started TRT with the gel. After a couple weeks, I felt great. I was not chronically tired anymore, and I had energy to go out, exercise, etc. It lasted for a few weeks, during which my T went from 150 to a meager 300 using Labcorp's scale. Yet, I still felt ok.

Soon, I crashed. Did not want to get out of the bed, exercise, etc. It was even worse than before TRT. This is how I came to know Excelmale: I came hear for advice, and ended up hooking up with Defy. I found out that my SHBG is low, and ended up in a daily propionate regimen, which I started about 2 months after my crash started.

I've been in this regimen for 10 days and now I'm starting to feel great again.

Here's my big worry: will I crash again?
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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