Salivary DHEA vs plasma DHEA-S?

[Gianluca]

I was just measured my salivary DHEA in an adrenal stress test, the level came back quiet low, 32pg/ml on a scale 137-336

I’m on 15mg DHEA supplement, which generally brings my DHEA-S at about 400, I’m confused about the result of the salivary test.

which test between the two is more accurate?

 

[JA Battle]

There is at least a hundred times more dheas in circulation than actual dhea. The primary one secreted from the adrenals is dheas. Not sure what your salivary test means, however dhea levels can fluctuate through the day. Dheas has virtually no fluctuations. Supplemental Dhea is rapidly metabolized into other hormones/dheas. In my opinion supplemental dhea is the wrong way to go about it. When I want to supplement, I supplement dheas in dmso. 1mg per drop.

 

[Gianluca]

There is at least a hundred times more dheas in circulation than actual dhea. The primary one secreted from the adrenals is dheas. Not sure what your salivary test means, however dhea levels can fluctuate through the day. Dheas has virtually no fluctuations. Supplemental Dhea is rapidly metabolized into other hormones/dheas. In my opinion supplemental dhea is the wrong way to go about it. When I want to supplement, I supplement dheas in dmso. 1mg per drop.

I figured the reason for this. Salivary DHEA measure the free form of hormone, despite my DHEA-S is optimal, the free form is low, I will follow up this with my doc