Recent bloodwork - Love feedback

pyater

Member
Recent Blood work summary - started compound cream on 2/26/201 - see protocol below.

Bloodwork from last week - 9 weeks after TRT restrart with cream.

Testosterone, Serum >1500 ng/dL H
Free Testosterone 41.5 pg/mL H
Insulin-Like GF-1 274 ng/mL H
Prolactin 20.9 ng/mL

Hemoglobin A1C 5.3 %
LH <1.0 mIU/mL LOW
FSH 0.1 mIU/mL

TSH 1.760 mcU/mL
Free T4 1.21 ng/dL
Cholesterol 90 mg/dL
Triglycerides 79 mg/dL
HDL 28 mg/dl LOW
LDL Calculated 46 mg/dL
Glucose 97 mg/dL
DHEA 299.7
Vitamin D - 25 Hydroxy 29.7 LOW
Estradiol, Sensitive 64.7 HIGH
SHBG 21.9

Protocol
Testosterone 200mg/ml CREAM - apply 2 clicks directly to scrotum every AM + 1 click directly to scrotum every night
NO HCG
Anastrozole 0.125mg by mouth 3 times weekly to be taken ONLY if experiencing high E symptoms
Metformin 500mg ER tab by mouth twice daily
Tadalafil 25mg ODT - take 1/4 ODT sublingual daily for

Once I saw the results, I went to one click in the AM and 1 in PM . Also have taken the AI this week after the Estradiol results that just came in but was not prior to test. Feeling good, some swelling in feet, maybe some moodiness. Scheduling Pituitary MRI at the recommendation of Dr. Saya and Endocrinologist. Still waiting for DHT results and will schedule first follow with Dr. Saya.

Looking for feedback. Still trying to dial in cream protocol. Switched from Urologist to Defy in Feb and switched to cream.

Thoughts and feedback?
 
Recent Blood work summary - started compound cream on 2/26/201 - see protocol below.

Bloodwork from last week - 9 weeks after TRT restrart with cream.

Testosterone, Serum >1500 ng/dL H
Free Testosterone 41.5 pg/mL H
Insulin-Like GF-1 274 ng/mL H
Prolactin 20.9 ng/mL

Hemoglobin A1C 5.3 %
LH <1.0 mIU/mL LOW
FSH 0.1 mIU/mL

TSH 1.760 mcU/mL
Free T4 1.21 ng/dL
Cholesterol 90 mg/dL
Triglycerides 79 mg/dL
HDL 28 mg/dl LOW
LDL Calculated 46 mg/dL
Glucose 97 mg/dL
DHEA 299.7
Vitamin D - 25 Hydroxy 29.7 LOW
Estradiol, Sensitive 64.7 HIGH
SHBG 21.9

Protocol
Testosterone 200mg/ml CREAM - apply 2 clicks directly to scrotum every AM + 1 click directly to scrotum every night
NO HCG
Anastrozole 0.125mg by mouth 3 times weekly to be taken ONLY if experiencing high E symptoms
Metformin 500mg ER tab by mouth twice daily
Tadalafil 25mg ODT - take 1/4 ODT sublingual daily for

Once I saw the results, I went to one click in the AM and 1 in PM . Also have taken the AI this week after the Estradiol results that just came in but was not prior to test. Feeling good, some swelling in feet, maybe some moodiness. Scheduling Pituitary MRI at the recommendation of Dr. Saya and Endocrinologist. Still waiting for DHT results and will schedule first follow with Dr. Saya.

Looking for feedback. Still trying to dial in cream protocol. Switched from Urologist to Defy in Feb and switched to cream.

Thoughts and feedback?
Not sure what you mean when you say dialing in. It sounds like you were fairly happy with the way you felt. With your high t and free t your estradiol numbers are okay, a little high. More importantly if you feel good with that protocol. Did you feel better after taking the AI?

My shbg is similar to yours and I would have serious e symptoms with free t that high.
 
So just the water retention and moodiness. But feet are pretty swollen. No nipple issues or anything. Not yet with the AI but its only been two doses.

What other e symptoms would I be looking for?
 
I think you made a good call to reduce the dosing to 1 and 1, >1500 isn't a sustainable level. I wouldn't use the AI, yet, and isolate your change to just the one thing, the dose reduction.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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