Questions on HCG

Diablo666

Member
Hi Dear forum members,

I am starting HCG Monotherapy as I am secondary, wanting to preserve fertility and leaving TRT as a last resource. I was previously on clomid for 4 months with zero libido. Went off from clomid for 2.5 weeks and still zero libido (natural state). Yesterday I had my first shot subQ at 500IU (my protocol is 3x week at 500IU each) and I did not notice anything different. So I have a few questions:

1. Should I expect a decent improvement in libido from HCG mono?
2. Why people say effects on HCG only lasts like 1 day, if HCG is supposed to stimulate testosterone production, but I thought Testosterone has a half life of 7 days, so should not be the case that I get a shot of HCG and the extra testosterone that my testes produce will last for at least a few days and so on?
3. How long does testosterone take in being produced? I know sperms can take up to 90 days, but have not found how long does testosterone take?
4. Is it possible that I will need to try HCG at least a few weeks to start getting results?

Thanks,
 
1.) You won't know this until you've been on it for 6 weeks and have new labs done.
2.) Nelson has a research article showing that 500iu of HCG last 3 days. Most of us that use it concur with his findings.
3.) same answer as #1, labs will tell the story.
4.) Yes
5.) Everyone has a different response to TRT or HCG so only with time and future labs you will eventually learn. Patience is the key.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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