crazycanuck
Member
Been awhile since I posted so I figured I would come back with a question to test everyone. I'm actually hoping that Nelson might have an opinion on this.
I am secondary Hypogonadism brought on by Hereditary Hemochromatosis and have been on TRT for over a year. My current protocol is 150mg of Test E (75 twice a week), 300iu X2 per week and this has put me at the 950 ng/dl range consistently. All labs are right on mark with the exception of LDL as a result of a keto based lifestyle. So, TRT wise, I feel pretty dialed in.
For the HH side of things (for those that don't know what it is, it is a genetic iron overload situation), it's a mess. I am running low ferritin and iron levels but my Transferrin Saturation level (TSAT%) has me hovering around 60, which isn't safe and means that my body is storing too much iron. This despite being on a 500ml blood draw every 6 weeks.
About 4 weeks ago, I began displaying high estrogen symptoms (itchy nipples, sensitive and joint pain - which also have some similarities to HH symptoms, minus the sensitive nipples) so I went to my Urologist. He prescribed Arimidex as a precaution and sent me for labs. started the Arimidex and a few days later, the labs came back with T in the 980 range, E2 (non sensitive in Canada) at 146. Not wanting to crash my E2, I stopped the Arimidex pending a follow up.
A week later, I had to get labs for my HH and my TSAT % came in at 13 and a weeks later it was 23. Fast forward to today, 3 weeks off Arimidex, I got bloods drawn for HH. My TSAT% is already up to 57.
I've been searching for a causation link to the drop and Arimidex with only a few articles pertaining to a side effect noted as Arimidex Anemia for cancer patients. So my questions are:
1) has anyone experienced or is aware of Arimidex having this effect in the TRT world?
2) given the possibility that Arimidex might be my saving grace, not so much for E2 but more for an uncontrolled TSAT %, is it feasible to run at a higher T level to allow for long term Arimidex usage i.e cause greater aromatization to keep from crashing E2?
3) at .25mg once or twice a week, how long would it take for the more negative aspects of Arimidex to show?
I am secondary Hypogonadism brought on by Hereditary Hemochromatosis and have been on TRT for over a year. My current protocol is 150mg of Test E (75 twice a week), 300iu X2 per week and this has put me at the 950 ng/dl range consistently. All labs are right on mark with the exception of LDL as a result of a keto based lifestyle. So, TRT wise, I feel pretty dialed in.
For the HH side of things (for those that don't know what it is, it is a genetic iron overload situation), it's a mess. I am running low ferritin and iron levels but my Transferrin Saturation level (TSAT%) has me hovering around 60, which isn't safe and means that my body is storing too much iron. This despite being on a 500ml blood draw every 6 weeks.
About 4 weeks ago, I began displaying high estrogen symptoms (itchy nipples, sensitive and joint pain - which also have some similarities to HH symptoms, minus the sensitive nipples) so I went to my Urologist. He prescribed Arimidex as a precaution and sent me for labs. started the Arimidex and a few days later, the labs came back with T in the 980 range, E2 (non sensitive in Canada) at 146. Not wanting to crash my E2, I stopped the Arimidex pending a follow up.
A week later, I had to get labs for my HH and my TSAT % came in at 13 and a weeks later it was 23. Fast forward to today, 3 weeks off Arimidex, I got bloods drawn for HH. My TSAT% is already up to 57.
I've been searching for a causation link to the drop and Arimidex with only a few articles pertaining to a side effect noted as Arimidex Anemia for cancer patients. So my questions are:
1) has anyone experienced or is aware of Arimidex having this effect in the TRT world?
2) given the possibility that Arimidex might be my saving grace, not so much for E2 but more for an uncontrolled TSAT %, is it feasible to run at a higher T level to allow for long term Arimidex usage i.e cause greater aromatization to keep from crashing E2?
3) at .25mg once or twice a week, how long would it take for the more negative aspects of Arimidex to show?
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