Q's about backfilling pathways (T, dhea, preg)

Vvs1

Active Member
When we try to backfill the pathways, how long is necessary to supplement?

My Dhea was low last year, and Defy gave me an Rx of Dhea and Preg. On the next test, my Dhea was way above normal range. Is this enough to backfill, or is it necessary to continue a lower dose supplement?

One more question, is Testosterone a hormone that can fall behind or backfill?
 
Assuming you're doing well on everything (free of sides), they all need to be continued at the doses they've recommended.
It's not something you start and stop.

Not sure exactly what you mean can testosterone fall behind or backfill...........??
 
Sean's question is a good one. What do you mean about testosterone falling behind and backfilling? Once you start a testosterone replacement protocol, your body shuts down all natural production of the hormone. You are replacing this necessary hormone.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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