Perfect Labs - Libido , ED, GARBAGE! On Trimix! Why?

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audiognostic

New Member
Thank you guys, I have posted this before, but it is worth it to post it again as I desparately need some help and i do not trust any doctors at this point, what is happening is I have been on TRT for 2+ years now, my libido is up and down , my ED is terrible 90% of the time and 10% of the time things are great all the sudden, 90% of the time i dont have morning wood, 10% of the time i do all the sudden, i have basically no sensitivity when i am having these issues.. I have tried raising my dose up and down, I have raised my DHT through cream, I have taken cypionate bi weekly, every other day, every day, went to propionate.. taken anastrozole different doses.,NOTHING gives me consistent results, yet, I know i do not have a physical problem with my genitals or something because I have had those times when things were great! ANY suggestions? WTF

REGIMEN:
Daily Propionate IM Injection 12mg

LABS:
Testosterone total: 733 (350-100)
Testosterone free 21.9 (9.3-26.5)
SHBG 22 (10-57)
E2 sensitive 37 (8-35)
DHEA S 254.1 (138-475)
Progesterone 0.4 (0.0-0.5)
Prolactin 8.1 (4-15.2)
DHT 50 (30-85)

Free T3 (thyroid ) 4 (2-4.4)
TSH 2.17 (0.45-4.5)
A1C (diabetes) 5.2 (4.8-5.6)
Total Cholesterol 127 (low)
 
Defy Medical TRT clinic doctor
Have you kept a log of when you felt good - the 10% ? Perhaps that might yield some clues. I always find it useful to lookup my food/mood/supplement log anytime i veer of course.

Are you following some kind of diet - i ask because of the the low Cholesterol and relatively high Tsh. How is you body fat and health overall other than the ed/libido. Frankly, the numbers while fitting nicely in range may not be "perfect" for you. Adding in some Dhea may be useful too. How long did you use the cream - was it alone or with injection?
 
For me, libido and erections have always been more with my brain than my hormones. I tend to have high norepinephrine and things life coffee, stimulants will often kill any chance of an erection. I oddly can take a small dose of an SSRI and get great sexual response from it.

I'm not suggesting this will work for you, or anyone else. However, I would look more into your neurotransmitters and how they affect your sex drive and performance. Your hormones look solid.
 
Agree with getting your FreeT above 30 and also getting more thyroid labs. Specifically ft4 and rT3 as your TSH is out of optimal range.



What is it you are having trouble understanding here?



He stated:


Thank you guys, I have posted this before, but it is worth it to post it again as I desparately need some help and i do not trust any doctors at this point, what is happening is I have been on TRT for 2+ years now, my libido is up and down , my ED is terrible 90% of the time and 10% of the time things are great all the sudden, 90% of the time i dont have morning wood, 10% of the time i do all the sudden, i have basically no sensitivity when i am having these issues.. I have tried raising my dose up and down, I have raised my DHT through cream, I have taken cypionate bi weekly, every other day, every day, went to propionate.. taken anastrozole different doses.,NOTHING gives me consistent results, yet, I know i do not have a physical problem with my genitals or something because I have had those times when things were great! ANY suggestions? WTF
 
What is it you are having trouble understanding here?



He stated:


Thank you guys, I have posted this before, but it is worth it to post it again as I desparately need some help and i do not trust any doctors at this point, what is happening is I have been on TRT for 2+ years now, my libido is up and down , my ED is terrible 90% of the time and 10% of the time things are great all the sudden, 90% of the time i dont have morning wood, 10% of the time i do all the sudden, i have basically no sensitivity when i am having these issues.. I have tried raising my dose up and down, I have raised my DHT through cream, I have taken cypionate bi weekly, every other day, every day, went to propionate.. taken anastrozole different doses.,NOTHING gives me consistent results, yet, I know i do not have a physical problem with my genitals or something because I have had those times when things were great! ANY suggestions? WTF
He obviously is changing too much and not letting things settle before changing again. Raising free T to 30, which is a more optimal range, keeping it there, and fixing thyroid would most likely help. But you know that right? Oh and you also noticed his dhea and cholesterol is low right? No you didn't, you decided to attack me instead. Don't like my suggestions skip it then, you're not helping
 
Here is his labs from a previous thread he started in March!




Total T 916

Free T 24.5 (2.7%)

E2: 37 (AI doesnt seem to help and only makes things worse, ive tried arimidex and aromasin)

SHBG: 23 ( a little on the low end, but nothing like i see "low shbg guys" struggling with in the teens and stuff)

DHT: 50 (tested about 2 years ago after starting trt still feel the same now)

Prolactin : 8 (not high at all)

Progesterone looks normal.

Thyroid, diabetes markers, all look good and normal

no other major health issues




As you can see although looking at his labs with a TT 916 ng/dL and SHBG 23 nmol/L.....that although his FT is not at the top end of the range that number is misleading to most!

Why......because he had the wrong assay done when testing his FT as the piss poor direct immunoassay which has shown to be inaccurate let alone no longer recommended was used.......let alone underestimates FT when compared to the gold standard Equilibrium Dialysis.

Unfortunately most are still using/relying on this inaccurate assay when testing their FT levels which is a waste of time.

The only way to truly know where ones FT levels sit on such protocol (T dose/injection frequency) is to have it tested using the most accurate assay which is the gold standard Equilibrium Dialysis or Ultrafiltration (next best) or to simply use the newer calculated TruT method (which has been shown to be on par with results obtained by the gold standard ED) and is available online for free to the general public.

TruT Free Testosterone Calculator by FPT


Using the newer calculated TruT method.....if we take his TT 916 ng/dL, SHBG 23 nmol/L, Albumin 4.3 g/dL than his FT would be 33.65 ng/dL (just over the top end of the reference range 16-31 ng/dL).
Screenshot (546).png


His FT levels on such protocol (T dose/injection frequency) is already in the 33 ng/dL range (just over the top end) and that is at trough!

Could he increase his FT levels a little more.....sure but highly doubtful his FT levels are the issue.




Even on this most recent protocol with a TT 733 ng/dL, SHBG 22 nmol/L, Albumin 4.3 g/dL (mean) than using the newer calculated TruT his FT would be 26.62 ng/dL (just over mid-range of the reference range of 16-31 ng/dL).
Screenshot (547).png




Now one can definitely say bring your TT up to get your FT levels up into the top end/slightly over as in 30+ ng/dL.....but again as he already stated he has tried a higher dose and I have just shown you where his FT levels sat at such dose.....so he has already tried a dose of T which put his FT (trough) levels in the 33 ng/dL range.

https://tru-t.org/
 
Here is his labs from a previous thread he started in March!




Total T 916

Free T 24.5 (2.7%)

E2: 37 (AI doesnt seem to help and only makes things worse, ive tried arimidex and aromasin)

SHBG: 23 ( a little on the low end, but nothing like i see "low shbg guys" struggling with in the teens and stuff)

DHT: 50 (tested about 2 years ago after starting trt still feel the same now)

Prolactin : 8 (not high at all)

Progesterone looks normal.

Thyroid, diabetes markers, all look good and normal

no other major health issues




As you can see although looking at his labs with a TT 916 ng/dL and SHBG 23 nmol/L.....that although his FT is not at the top end of the range that number is misleading to most!

Why......because he had the wrong assay done when testing his FT as the piss poor direct immunoassay which has shown to be inaccurate let alone no longer recommended was used.......let alone underestimates FT when compared to the gold standard Equilibrium Dialysis.

Unfortunately most are still using/relying on this inaccurate assay when testing their FT levels which is a waste of time.

The only way to truly know where ones FT levels sit on such protocol (T dose/injection frequency) is to have it tested using the most accurate assay which is the gold standard Equilibrium Dialysis or Ultrafiltration (next best) or to simply use the newer calculated TruT method (which has been shown to be on par with results obtained by the gold standard ED) and is available online for free to the general public.

TruT Free Testosterone Calculator by FPT


Using the newer calculated TruT method.....if we take his TT 916 ng/dL, SHBG 23 nmol/L, Albumin 4.3 g/dL than his FT would be 33.65 ng/dL (just over the top end of the reference range 16-31 ng/dL).
View attachment 8204

His FT levels on such protocol (T dose/injection frequency) is already in the 33 ng/dL range (just over the top end) and that is at trough!

Could he increase his FT levels a little more.....sure but highly doubtful his FT levels are the issue.




Even on this most recent protocol with a TT 733 ng/dL, SHBG 22 nmol/L, Albumin 4.3 g/dL (mean) than using the newer calculated TruT his FT would be 26.62 ng/dL (just over mid-range of the reference range of 16-31 ng/dL).
View attachment 8205



Now one can definitely say bring your TT up to get your FT levels up into the top end/slightly over as in 30+ ng/dL.....but again as he already stated he has tried a higher dose and I have just shown you where his FT levels sat at such dose.....so he has already tried a dose of T which put his FT (trough) levels in the 33 ng/dL range.

TruT Free Testosterone Calculator by FPT
Thank you for showing me how smart you are, thoroughly impressed. Unfortunately the OP needs help but you would rather waste time trying to impress me. His thyroid is not optimal. He needs to remain consistent with his testosterone treatment, optimize thyroid, optimize dhea, and figure out why cholesterol is low. But hey, I appreciate you showing me how smart you are with the Google machine.
 
He obviously is changing too much and not letting things settle before changing again. Raising free T to 30, which is a more optimal range, keeping it there, and fixing thyroid would most likely help. But you know that right? Oh and you also noticed his dhea and cholesterol is low right? No you didn't, you decided to attack me instead. Don't like my suggestions skip it then, you're not helping


Raising free T to 30, which is a more optimal range, keeping it there,

- he has already been there and done that......but you knew that right from looking over his previous threads.....LOL!


Oh and you also noticed his dhea and cholesterol is low right?

- indeed I did and highly doubtful it is causing extreme ED......if anything one should be looking deeply into vascular/endothelial dysfunction when suffering from extreme ED!

- he has tried pde-5 inhibitors already to no avail

- from his previous thread:On TRT, good looking numbers, horrible ED and no morning wood STILL.. help

- he clearly stated "its really bad, 100 mg viagra barely helps and 20 cialis barely does anything"

- now he is using trimix and still struggling
 
Thank you guys, I have posted this before, but it is worth it to post it again as I desparately need some help and i do not trust any doctors at this point, what is happening is I have been on TRT for 2+ years now, my libido is up and down , my ED is terrible 90% of the time and 10% of the time things are great all the sudden, 90% of the time i dont have morning wood, 10% of the time i do all the sudden, i have basically no sensitivity when i am having these issues.. I have tried raising my dose up and down, I have raised my DHT through cream, I have taken cypionate bi weekly, every other day, every day, went to propionate.. taken anastrozole different doses.,NOTHING gives me consistent results, yet, I know i do not have a physical problem with my genitals or something because I have had those times when things were great! ANY suggestions? WTF

REGIMEN:
Daily Propionate IM Injection 12mg

LABS:
Testosterone total: 733 (350-100)
Testosterone free 21.9 (9.3-26.5)
SHBG 22 (10-57)
E2 sensitive 37 (8-35)
DHEA S 254.1 (138-475)
Progesterone 0.4 (0.0-0.5)
Prolactin 8.1 (4-15.2)
DHT 50 (30-85)

Free T3 (thyroid ) 4 (2-4.4)
TSH 2.17 (0.45-4.5)
A1C (diabetes) 5.2 (4.8-5.6)
Total Cholesterol 127 (low)


You have already tried pde-5 inhibitors which were not effective.....now you are using trimix and still struggling with severe ED.

I would be looking into vascular/endothelial dysfunction.

Have you ever had testing done through a urologist?
 
Raising free T to 30, which is a more optimal range, keeping it there,

- he has already been there and done that......but you knew that right from looking over his previous threads.....LOL!


Oh and you also noticed his dhea and cholesterol is low right?

- indeed I did and highly doubtful it is causing extreme ED......if anything one should be looking deeply into vascular/endothelial dysfunction when suffering from extreme ED!

- he has tried pde-5 inhibitors already to no avail

- from his previous thread:On TRT, good looking numbers, horrible ED and no morning wood STILL.. help

- he clearly stated "its really bad, 100 mg viagra barely helps and 20 cialis barely does anything"

- now he is using trimix and still struggling
Instead of trying to impress me with your smarts, try using Google machine to fix his ED and hypocholesterolemia.

Hypercholesterolemia-induced erectile dysfunction: endothelial nitric oxide synthase (eNOS) uncoupling in the mouse penis by NAD(P)H oxidase
 
Beyond Testosterone Book by Nelson Vergel
Thank you for showing me how smart you are, thoroughly impressed. Unfortunately the OP needs help but you would rather waste time trying to impress me. His thyroid is not optimal. He needs to remain consistent with his testosterone treatment, optimize thyroid, optimize dhea, and figure out why cholesterol is low. But hey, I appreciate you showing me how smart you are with the Google machine.


No one trying to impress here.....far from it!

Vascular disease is multifaceted and cholesterol is only one piece of the puzzle.....he has been suffering from severe ED for some time.....his cholesterol is low as of now......how has it been over the past years?
 
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