New Labs...wrong E2 assay?

JimBob

Active Member
Not sure about this E2 test. I ordered the sensitive assay, which confused the phlebotomist at the hospital. She said she'd never seen such an assay. Clearly, my blood sugar needs attention. Maybe I'll be a candidate for metformin? I think it's genetic since my mother is type II. I'm far from being obese, too. I'll need to do more research on the cholesterol numbers before I get too concerned. Keto put everything higher, including HDL. FYI, I'm not on TRT.

TT 642 240-950
FT 12.8 3.67-13.9
SHBG 51 10-57
Estradiol-Routine [130999776] (Normal)
Estradiol <20 0-47
DHEA 166 24-244
A1C 5.9 4.3-6.1
Estimated Average Glucose 123
Insulin 4.0 2.0-23.0
PSA 1.14 0-4.0
TSH 1.65 .45-5.33
T3, FREE 3.0 2.5-3.9
T4, FREE 1.0 .6-1.2
Triglyceride 91 30-149
Cholesterol 348 <200
HDL 91 >40
LDL 239 <100
Lipoprotein A 31 <30

Comprehensive Metabolic Panel
Glucose 115 80-99
 
Well, having done a bit of reading, the elevated Lip-A is my main concern, followed by my elevated blood glucose. It doesn't appear there is much in the way of lifestyle changes that can affect the Lip-A. No drugs, either. Looks like I got stuck with shitty genes. The elevated blood glucose is also largely genetic, but metformin may be the answer for that. Who knows, maybe lowering my blood glucose will affect the Lip-A in a positive way? It will certainly reduce inflammation. I see my FNP soon.
 
With the numbers below, is there any way to increase my FT since I'm probably not a TRT candidate with a TT of 642?


TT 642 240-950
FT 12.8 3.67-13.9
SHBG 51 10-57
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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