New Blood Work - Does it Explain Weight Gain?

hfbjr

Member
Here's my latest blood work. My concerns are with my cholesterol. In addition to the weight gain I'm experiencing. It's going to the top of my stomach, not at the waist, like I'm forming a ball. Sorry for the double post. I'm injecting every day sub q 26 mgs of test. I also take arimidex as needed, and a half grain of naturethyroid. Also cabergoline. I've since lowered my test to 24 mls.

Glucose 84. 70-99
wbc. 9.5. 4.0- 11.0
rbc. 5.73h. 4.34- 5.60
hgb 17.4h. 13.0- 17.0
hct. 51.4h. 38.6- 49.2
Estaverage glucose 91.

T3,free. 4.28. 2.52- 4.34
t4,free. 1.09. 0.55-1.60
tsh. 1.043. 0.270-4.200
reverse t3. 30.9h. 9.0-27.0

total test. 1330h. 300-1080

free test 408h. 47- 244

igf1 252. 132-333

estrodiol by tms 44.6h 10-42.0

prolactin 3.5. 2.64-13.13

dhea sulphate 262.9 70.0 -495
Shb glob. 30.20. 13.30-89.50

triglycerides 124. <150
cholesterol 139. <200
hdl cholesterol 39L. <40
non hdl cholesterol. 100 <130
Ldl calculated 75. 0-129
Chol. Hdl ratio 3.6. <=5
vldl calculated 25. 5-30
 
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How do you dose your AI "as needed?" Is that estradiol value the result of the sensitive test? I'm not familiar with the notation associated with it.
 
ALong with CW's remark on the E testing, what do you see wrong with your Cholesterol numbers? Low HDL is extremely common in TRT, if HDL is your question.
 
The value is the wrong test. Every time I go for lab work, the place gives the wrong test, even after I tell them give me the sensitive test
 
I meet with the doc via phone on the 15th. I was concerned that maybe I was becoming diabetic.or having issues with insulin. We shall see. I've lowered my dose of testosterone, it's been about 3 weeks and everything is fine.

Other concern is my elevated t3. We shall see.
 
to help getting the right test, when I sit down at Quest labs they enter everything and present me a sheet and ask me to verify my personal info, but at the bottom is the list of tests that they entered and I always check that, too, and point out the error.
 
Yeah, your RT3/FT3 ratio is low at 13.85. Based on where your FT4 sits on the reference range, compared to FT3 being over the top of the reference range, the initial speculation is that you're pooling; meaning your FT3 is just building up and not effectively reaching the cells in your body.

When FT3 starts to pool, the body compensates and shifts the T4 to convert at a higher rate of Reverse T3. The body will also increase RT3 at times when you're sick, so it's a little more easily understood why all the energy goes out the door when you have the flu.

Similar in contrast, when FT3 starts pooling, the body knows something is wrong, so as a method of regulation, and as stated to conserve resources, the shift to RT3 is in play until things normalize. In your case, you are adding NDT, not much, but it does have T3, so any exogenous form of T3 is going to have an impact.

I would suggest reviewing your total iron serum, ferritin, TIBC, and cortisol is also a KEY variable with how FT3 functions. If you haven't ran cortisol, the gold standard for evaluating will be a 4x saliva panel with DHEA correlation. Other areas like D3 and various parts of the electrolyte panel will/play a role, but the previous items listed are significant! Also, have you been ruled out for Hashis with both TPO and TgAb?
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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