Moving from gel to cypionate - do you guys feel better on injectables?

trtthings

Active Member
I'm going to ask a questions that have been asked a bunch of times before.

I'm moving from gel to cypionate, even though my levels on the gel are reasonable.

A few things:
* I seem to be very sensitive to medium-high levels of E2
* I have high levels of SHBG.

1. Have any of you felt that you did much better on injections than on the gel? And in what ways? (And were you getting okay levels with the gel?)

2. Dosing for low E2 and high SHBG. If I recall.. high doses drive down SHBG but raise E2.
- I know blood tests are required. Is 40mg EOD excessive to start at?

3. I see some complain of higher E2 and DHT from subq. This contradicts the fact that you shouldn't be able to aromatise the ester until it's in the bloodstream (but in line with what the gel does, which goes through a layer of fat - but without an ester). Is IM a reasonable place to start at? Is there anyone here who felt noticeably better on subq or is it just a convenience thing?

I did get HCG prescribed as well but I will not be taking it at the beginning. I feel like things are already complicated enough with T and the AI.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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