MK-677

Johnny Test

Active Member
Anyone know if I need to taper off MK-677 when I decide to discontinue it? I’ve been on 5 weeks and am going to stop it after 8 weeks. I’m at 25mg a day. Thanks in advance.
 
Not really. That’s why I’m giving it a few more weeks. It’s making me ridiculously hungry all of the time which is becoming extremely annoying.
 
Note that you're keeping your pituitary pegged on high-HGH which is totally un-natural and one of the reasons it was never approved. I would think you would want to come off as quickly as possible. The Doctors who recommend similar compounds suggest only using them intermittently.
 
Note that you're keeping your pituitary pegged on high-HGH which is totally un-natural and one of the reasons it was never approved. I would think you would want to come off as quickly as possible. The Doctors who recommend similar compounds suggest only using them intermittently.
How intermittently and at what dose are these recommendations? Also, I thought MK-677 was still in trials. Is that no Longer the case?
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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