Metformin and insomnia

grayiron

New Member
I’m taking metformin 500 morning and night. For anti aging purposes only. Im not diabetic. My a1c is 5. The problem I’m having taking before bed keeps me awake for hours. Has anyone else had this? I may just take it once a day only
 
I would try the ER version as Vince said, or take one of your 500 mg pills with breakfast and the other with dinner instead of before bed.
 
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I doubt that metformin is causing this issue. I would look elsewhere. Do you supplement magnesium? It helps me a lot.
 
That was a while back, I was conducting an experiment. Yes I do take magnesium. I have been taking that supplement at night for 10 plus years. I continue to suffer from sleep issues. That’s one issue I have yet to find a solution. Started as I passed 55. Lol
 
Melatonin, valerian root, lemon balm, gaba, kava kava, u name it. I’m research scientist. All help but nothing is a sure knock down winner. It running several companies at the same time is root of all evil. No that’s money, same thing. Lol
 
I've heard that 5-HTP, Theanine, and Passion Flower assist in better sleep but I have never tried them.
 
Actually I have tried Beverly Meyers brand Passion flower and I currently take 5-htp and theanine. 6 hours is currently the max sleep I can get
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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