Maximus: Oral TRT+ (native T + enclomiphene + pregnenolone)

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Today we’re excited to announce a breakthrough in men’s hormone optimization: Maximus' Oral TRT+ Protocol. Testosterone, without injections or messy creams, all while maintaining fertility markers.

Timestamps:

0:00 - 0:09 - Introduction
0:10 - 3:54 - What is Maximus Oral TRT+?
3:55 - 4:44 - Maximus' Clinical Study Results & Findings
4:45 - 8:09 - Benefits Of Oral TRT+
8:10 - 9:54 - Getting Started On Oral TRT+
9:55 - 10:36 - Is Oral TRT+ Liver & Kidney Safe?
10:37 - 11:41 - How is Oral TRT+ Safe on Fertility Markers?
11:42 - 15:53 - Oral TRT+ Vs Injectable TRT
15:54 - 17:04 - How long does it take Oral TRT+ to start working?
17:05 - 18:18 - Do I need to donate blood on Oral TRT+?
18:19 - 19:37 - Will Oral TRT+ Give me Gynecomastia?
19:38 - Why This Is A Game-changer in mens TRT.

• 00:00 Overview of Maximus Oral TRT+ Protocol
  • Introduction to Maximus Oral TRT+ Protocol, a combination of oral native testosterone and enamine.
  • Explanation of native testosterone and its distinction from testosterone esters used in traditional TRT.
  • Description of enamine as a selective estrogen receptor modulator (SERM) and its benefits in increasing testosterone levels without the side effects of other medications.
• 02:18 Synergy and Benefits of Maximus Oral TRT+ Protocol
  • Explanation of the synergy between native testosterone and enamine in mitigating the suppression of LH and FSH levels.
  • Benefits of the protocol include significant increases in testosterone levels, improvements in energy, mood, sexual functioning, body composition, and recovery.
  • Clinical trial results showing multiple-fold increases in testosterone levels and improvements in various aspects of well-being for participants.
• 04:55 Side Effects and Management
  • Discussion on rare and mild side effects, including increased DHT levels and potential hair loss or acne exacerbation.
  • Introduction of dutasteride as a solution for managing DHT-related side effects.
  • Offer of oral dutasteride as an adjunct to the Maximus Oral TRT+ Protocol.
• 08:21 Process for Getting Started
  • Explanation of the process for starting the protocol, including filling out an online assessment, receiving an at-home blood test kit, and consultation with a doctor.
  • Overview of ongoing monitoring and support provided by the clinical care team.
  • Assurance of safety regarding liver, kidney, and testicular function, with explanations supported by research studies.
• 10:38 Frequently Asked Questions
  • Addressing common questions about the protocol, including its effects on liver and kidney function, testicular function, and fertility.
  • Explanation of why the protocol is considered superior to traditional TRT in terms of convenience, hormonal balance, and long-term health considerations.
  • Reassurance regarding the low likelihood of side effects such as polycythemia and gynecomastia with the Maximus Oral TRT+ Protocol.

 

Will do. I have been surfing different forums and I have found a few anecdotes where people have been running enclomiphene with their cypionate and have mid-high lh/fsh. I am going to continue with my protocol (Prop) but drop the HCG because I don't like it anyway and switch to enclomiphene which I have some from Hallendale. I will get tested in about a month and let yall know how it goes. Plan on taking 12.5mg enclomiphene eod at night time.

I'm having trouble finding the video but Dr. Mark Gordon uses clomid with his patients and he says it works to raise lh/fsh while on TRT.

I've never seen a SERM able to raise LH/FSH to baseline levels while on injectable TRT. Dr. Justin Saya has noted this numerous times as well on discussion forums. Maybe a little bit, but not avoiding suppression altogether.

 

what GH secretagogue would you recommend?

Testosterone:

Testosterone administration increases insulin-like growth factor-I levels in normal men - PubMed

Although testosterone (T) administration can increase insulin-like growth factor-I (IGF-I) when administered to hypogonadal men, no studies have examined whether this occurs in normal men. The present study was undertaken to determine if an increase in IGF-I may be part of the anabolic effect of...

pubmed.ncbi.nlm.nih.gov

That's why oral testosterone pairs well with enclomiphene.

 

The benefits, I noticed immediately were smoother sailing to a steady state in 7 days. No ups and downs like on injections, which goes on for weeks.

Definitely improvement in libido and erections, which was mostly absent on injections beyond the first week. Also Jatenzo nets you higher DHT than with injections.

I would try to aim for a higher than mid range at your midpoint or 6 hours.

Yesterday I got 592 ng/dL at 5 hours. Estrogen was 18 pg/mL and will rectify that now that I’ve stopped daily Cialis. I feel so much better after stopping daily Cialis!

592 ng/dL is not that high. What dose are you taking?

In our last trial, we saw peak Total T levels at 1327 ng/dL on average.

 

Wtf is "native testosterone"?

I'd assume they mean endogenous testosterone

 

I'd assume they mean endogenous testosterone

Native testosteorne, just like your body mades (unmodified, unesterified). The good stuff!

It's chemically identical to endogeonous T, but because the oral tablet doesn't come from endogenous sources, I wouldn't call it that. But the part stimualted by enclomiphene can be.

It's more testosterone reinforcement therapy vs. true replacement.

 

Re: Halotestin, see this study: Fluoxymesterone
They used small doses (average 2.5mg/day) in place of TRT. Testicle & penis size increased, and sperm parameters improved.

Re: Proviron, see this manufacturer's insert: https://www.bayer.com/sites/default/files/PROVIRON_EN_PI.pdf
It looks like it can be used to preserve fertility and as part (or replacement?) of TRT.

 

when will this be available in NY?

 

when will this be available in NY?

It became available in NY today.

 

anyone here with low T on this protocol? How has it been?

 

Hi, some questions regarding the new Oral Native Testosterone + Enclomiphene combo.
If someone can help me out with some wisdom (e.g. @docc), awesome!

---

Baseline / Context:

• Healthy male, athletic, non obese, mid 30s
• Total cholesterol: ~100 (on low-dose statin + ezetimibe)
• Baseline:
• Total T: ~500 ng/dlLH: 4.9 IU/L, SHBG: 42 nmol/l
  • Total T: ~500 ng/dl
  • LH: 4.9
  • Estradiol: 20,2 pg/ml
  • SHBG: 42 nmol/l
• After 3 months of enclomiphene only (6 mg every 3 days):
  • Total T: ~850 ng/dl
  • LH: ~13 (reference range: IU/L 1,7 - 8,6 IU/L)
  • Estradiol: 43.6 pg/ml (reference range: 11,3 - 43,2 pg/ml)
  • SHBG: 80.5 nmol/l (reference range: 18,3 - 54,1 nmol/l)

---

Questions:

• What could be a good oral T dose added to enclo — 400 mg or 600 mg?
• What total T levels are realistic from that setup?
• Does 2x dosing help anything?
• If dosing 2x/day is beneficial:
  • How many hours later would you take the second dose?
  • Equal split or e.g. 70/30?
  • Does 2x dosing cause suppression? Or increase E2 conversion?
• I heard cholesterol below 130 might impair steroid production —
  would it make sense to add pregnenolone because of this?

---

Thanks very much!

 

You left out a key factor free T.

 

Hi, some questions regarding the new Oral Native Testosterone + Enclomiphene combo.
If someone can help me out with some wisdom (e.g. @docc), awesome!

---

Baseline / Context:

• Healthy male, athletic, non obese, mid 30s
• Total cholesterol: ~100 (on low-dose statin + ezetimibe)
• Baseline:
• Total T: ~500 ng/dlLH: 4.9 IU/L, SHBG: 42 nmol/l
  • Total T: ~500 ng/dl
  • LH: 4.9
  • Estradiol: 20,2 pg/ml
  • SHBG: 42 nmol/l
• After 3 months of enclomiphene only (6 mg every 3 days):
  • Total T: ~850 ng/dl
  • LH: ~13 (reference range: IU/L 1,7 - 8,6 IU/L)
  • Estradiol: 43.6 pg/ml (reference range: 11,3 - 43,2 pg/ml)
  • SHBG: 80.5 nmol/l (reference range: 18,3 - 54,1 nmol/l)

---

Questions:

• What could be a good oral T dose added to enclo — 400 mg or 600 mg?
• What total T levels are realistic from that setup?
• Does 2x dosing help anything?
• If dosing 2x/day is beneficial:
  • How many hours later would you take the second dose?
  • Equal split or e.g. 70/30?
  • Does 2x dosing cause suppression? Or increase E2 conversion?
• I heard cholesterol below 130 might impair steroid production —
  would it make sense to add pregnenolone because of this?

---

Thanks very much!

Are you seeing hypogonadal symptoms? Your current total T levels are pretty good. Free T probably not as high due to the SHBG but if you are reaching symptom resolution on the current protocol then I would recomend not fixing what isnt broken.

If there are issues with the current protocol... what are they?

 

What could be a good oral T dose added to enclo — 400 mg or 600 mg?

Everyone is started on 600 mg, with the option to increase to 800 mg. If you wanted to start at 400 mg, that is something you could work out with your Maximus provider. The effective dosage can also be adjusted by varying the amount of co-ingested fat. For example, 600 mg taken with 20-30 g fat will produce lower levels than 50 g fat. 600 mg taken fasted will produce even lower levels.

What total T levels are realistic from that setup?

You'll find data on serum levels reached with different dosages, taken with and without fat in our white paper: https://www.maximustribe.com/white-paper/oral-trt

Does 2x dosing help anything?

Some patients experience a lull in the latter half of the day, so if you fall into that group, you may find a second dose is helpful.

If dosing 2x/day is beneficial:

• How many hours later would you take the second dose?
• Equal split or e.g. 70/30?
• Does 2x dosing cause suppression? Or increase E2 conversion?

A second dose is typically taken 6-8 hours after the first dose, in an equal split. Adding a second dose does cause additional suppression (but not additional E2) which can be countered with additional enclomiphene.

I heard cholesterol below 130 might impair steroid production —
would it make sense to add pregnenolone because of this?

This isn't a problem we've seen in practice, but it wouldn't be an unreasonable experiment. You'll want to consult with your Maximus provider on this though.

 

I thought I saw a post suggesting Empower could now compound Kyzratrex? Is that the case? If so I would assume Defy could prescribe it.