Lowering Test Dosage

[entreleader77]

I've been on HRT now for almost 6 years at a weekly dose of 200mg (cypionate). Up until about a 1.5 years ago my total T would average around the 800 mark. I switched to daily injections 1.5 years ago and my last 3 blood tests have my T levels at 1100-1200.

Since I'm over 1000, I think I would be OK dropping the dose down. I've been a week at 168 mg and I already feel less energy and lethargic. I'm hoping these symptoms will pass.

Has anyone lowered their dose and experienced similar effects? How long before it passed?

I'd love to get my dose down in half and hopefully be up there in the 600-800 range. I think it's far fetched but I have hopes.

BIGGEST REASON FOR DECREASE - My blood work (specifically my HDL/LDL) has gotten significantly worse over the past 6 years. I have noticed with the increase in T levels, an increase of aggression and lack of empathy.

 

[S1W]

In my experience, any protocol change throws things out of whack for several weeks. Seems like weeks 2-4 are always the hardest. That may be all that you're feeling.

That's the hardest thing about making protocol changes - even though we KNOW that it takes at least 45 days or so for things to settle in, it's too easy to second guess the protocol change when we're only a few weeks in and feeling off.

Best to commit to your change and wait at least 6-7 weeks and then evaluate how you feel.

 

[MarcoFL]

what does your free T run? SHBG? E2? how did you feel on the higher dose? did your doctor tell you to lower your dose?

 

[madman]

I've been on HRT now for almost 6 years at a weekly dose of 200mg (cypionate). Up until about a 1.5 years ago my total T would average around the 800 mark. I switched to daily injections 1.5 years ago and my last 3 blood tests have my T levels at 1100-1200.

Since I'm over 1000, I think I would be OK dropping the dose down. I've been a week at 168 mg and I already feel less energy and lethargic. I'm hoping these symptoms will pass.

Has anyone lowered their dose and experienced similar effects? How long before it passed?

I'd love to get my dose down in half and hopefully be up there in the 600-800 range. I think it's far fetched but I have hopes.

BIGGEST REASON FOR DECREASE - My blood work (specifically my HDL/LDL) has gotten significantly worse over the past 6 years. I have noticed with the increase in T levels, an increase of aggression and lack of empathy.

Forget about concentrating on where your TT level sits you need to be more concerned with where your FT levels sits and what is your SHBG?

Take the advice given @S1W

 

[entreleader77]

Forget about concentrating on where your TT level sits you need to be more concerned with where your FT levels sits and what is your SHBG?

Take the advice given @S1W

Free test is high as well - 31.5
SHBG - 27.9
DHT - 115
Estradiol, sensitive - 53.6 - before anyone freaks out on this number, just know, I feel best at around this level. No water retention, sensitive nipples, ED issues, or mood swings. I got down to 28 on AIs and felt terrible.

HDL - 32
LDL - 110
Triglycerides - 93

 

[HealthMan]

I've been on HRT now for almost 6 years at a weekly dose of 200mg (cypionate). Up until about a 1.5 years ago my total T would average around the 800 mark. I switched to daily injections 1.5 years ago and my last 3 blood tests have my T levels at 1100-1200.

Since I'm over 1000, I think I would be OK dropping the dose down. I've been a week at 168 mg and I already feel less energy and lethargic. I'm hoping these symptoms will pass.

Has anyone lowered their dose and experienced similar effects? How long before it passed?

I'd love to get my dose down in half and hopefully be up there in the 600-800 range. I think it's far fetched but I have hopes.

BIGGEST REASON FOR DECREASE - My blood work (specifically my HDL/LDL) has gotten significantly worse over the past 6 years. I have noticed with the increase in T levels, an increase of aggression and lack of empathy.

Totally normal to feel that way. Don't make any judgments on your new protocol now. Wait at least 6 weeks. If after 6-8 weeks you are still feeling off then try to tweak things