I'm in my early 40s. The free testosterone with equilibrium dialysis method is not available in my country. Total testosterone is 402 ng/dL The vermeulen equation after putting the Free testosterone (by CLIA) 15.7 pg/ml and SHBG 32.7 nmol/l, shows the following results
Are we dealing with significant T deficiency? There are symptoms of hypogonadism. LH 3.92 IU/L and FSH 4.65 IU/L. free androgen index 42%.
Assuming this is morning testosterone: Your cFTV result of 8 ng/dL is borderline. Some men do have symptoms at this level, even though it is considered to be within the normal range.
I would be hesitant to start conventional TRT without more information. If you have access to short-acting testosterone such as testosterone nasal gel then a trial may confirm hypogonadism by resolving your symptoms. Enclomiphene is another possibility, though results are less predictable.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
⚠️ Medical Disclaimer
This tool provides predictions based on statistical models and should NOT replace professional medical advice.
Always consult with your healthcare provider before making any changes to your TRT protocol.
ℹ️ Input Parameters
Normal range: 300-1000 ng/dL
Predicted Hormone Levels
Enter your total testosterone value to see predictions
Results will appear here after calculation
Understanding Your Hormones
Estradiol (E2)
A form of estrogen produced from testosterone. Important for bone health, mood, and libido.
Too high can cause side effects; too low can affect well-being.
DHT
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth,
prostate health, and masculinization effects.
Free Testosterone
The biologically active form of testosterone not bound to proteins.
Directly available for cellular uptake and biological effects.
Scientific Reference
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
