Low T or something else?

Jerome123 · 2025-09-09T20:52:17-0500

I’m 46, work out 5–6 days a week, 5’8”, 150 lbs (lean), hiv+ undetectable. For the last few years, I’ve had low libido, erection issues, fatigue, and poor sleep. Got labs done (results below).

Does this look like low testosterone, or could it be something else? Appreciate any feedback.

madman · 2025-09-09T22:01:31-0500

Jerome123 said:
I’m 46, work out 5–6 days a week, 5’8”, 150 lbs (lean), hiv+ undetectable. For the last few years, I’ve had low libido, erection issues, fatigue, and poor sleep. Got labs done (results below).

View attachment 52801

Does this look like low testosterone, or could it be something else? Appreciate any feedback.

Yes your FT is at the bottom end as in shitty!

Although TT is important to know FT is what truly matters as it is the active unbound fraction of testosterone responsible for the positive effects.

FT <5 ng/dL would be considered low.

FT 5-9 ng/dL would be considerd what we call the grey zone where some men may struggle with low-T symptoms.

FT 10-15 ng/dL would be healthy.

FT 20-25 ng/dL would be high-end/high.

The only way too know where your FT truly sits is testing it using the most accurate assay the gold standard Equilibrium Dialysis especially in cases of altered SHBG.

Even then you can still use/rely upon the linear law-of-mass action calculated.Vermeulen method which will give a good approximation just keep in mind that it tends to overestimated 20-30%.

Your FT was calculated using a modified Vermeulen equation.

You are hitting a TT 464 ng/dL with highish SHBG 43 nmol/L your FT is at the bottom-end of the reference range and your BAT is low.

Thread 'Re-evaluating the role of Free Testosterone and SHBG'

Sep 2, 2025

We do it big here at Nelson's stomping ground!

Dr. Leen Antonio (UZ Leuven)!

She has collaborated with the heavyweights in the field Dr. Bhasin and Dr. Jasuja (Brigham and Women's Hospital)), Dr. Fiers and team (UZ Ghent) on research related to free testosterone.