Low DHEA-S, in-range Testosterone/E2 levels

newmnton

New Member
Hi all.

I had these blood results taken earlier this year. I have a few questions, primarily around my very low DHEA-S levels. For context, I am a 27 year old male.

Follow up questions, are my testosterone levels alongside my estradiol readings any cause for concern?

For those who cannot see the document:
  • DHEA-S level is 2.7umol/L while the reference is 4.6-16.1
  • Free Testosterone is 501 pmol/L with reference 180-739
  • Estradiol 124pmol/L with reference 40-161
The only supplement/drug of note I’ve previously taken is MK-677 for a shoulder injury over lockdown. I do drink coffee (everyday) and chew nicotine gum (periods on and off for weeks at a time each).

I am open to seeing an endocrinologist, but am not convinced by doctors in my area. If you have any telemedicine options that are legally allowed to service international patients, that would be great too.

Thanks for any help!
 

Attachments

I don't see the reference range for the Total Testosterone. I only see the Estradiol above it. Your DHEA is low. What symptoms do you have?
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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