Labwork help - HCG Monotherapy?

Hey guys, I recently had some labwork done. 39 year old male, exercise daily, eat clean, plenty of sleep and hydration.
Here are the results (Labs taken at 8:45am, fasted)

Testosterone, Total: 421 Ref: 249-836 ng/dL
Testosterone, Free: 9.39 Ref: 4.5-23 ng/dL
Testosterone, Free %: 2.2
Estradiol: 27 Ref: 27-52 pg/mL
DHEA-S: 283.9 Ref: 88.9-427 ug/dL
Cortisol, Total: 9.6 Ref: 4.8-19.5 ug/dL
SHBG: 26.9 Ref: 16.5-55.9 nmol/L
IGF-1: 125 Ref: 53-331 ng/mL

FSH: 3.3 Ref: 1.5-12.4 mIU/mL
LH: 3.3 Ref: 1.7-8.6 mIU/mL
TSH: 1.45 Ref: .40-4.5 mIU/mL
T4: 1.6 Ref: .7-1.8 ng/dL
T3: 3.4 Ref: 2-4.4 pg/mL
Reverse T3: 12 Ref: 8-25 ng/dL
Thyroid Peroxidase Ab: 10 Ref: <35 IU/mL
Thyroglobulin Antibodies: 13 Ref: <115 IU/mL

*Note: all other labs were in good range, CBC, lipid profile, metabolic profile, etc..

My reason for going to the doctor was because I have very low energy, lack of motivation, negative thoughts, slight depression, brain fog, & feeling super blown out after workouts...The one thing I will say is that my libido seems to be fine, erections are solid.

I told my doc that I want to have kids in the near future so he suggested HCG Monotherapy (Clomid makes my eyes all jacked up). 500IU every day.

I trust this doctor but I really would like a second set of eyes on these labs/protocol. Never done HCG Monotherapy before. Having a normal libido is throwing me off, because the other symptoms are not tolerable anymore. Also nervous about jacking up my estrogen levels too high.

Would really appreciate any input or thoughts into this protocol. Thanks in advance!
 
That’s a good hCG protocol, maybe you need less.


Can you expand on this a little more?

Exercising too much can cause you to feel worn down all the time.
I train jiu jitsu 6am mon-thurs. We drill for 30 minutes and spar for 30 minutes. Nothing too crazy. I talked to the other guys and most do not feel blown out after training.

On a good week I’ll also lift weights 2-3x and maybe get a run in or hit the assault bike.

I rarely do two workouts in a day.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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